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. Author manuscript; available in PMC: 2024 Mar 21.
Published in final edited form as: Cell Rep. 2024 Feb 7;43(2):113746. doi: 10.1016/j.celrep.2024.113746

Figure 6. LA regulates the enhancer repertoire and reduces pro-inflammatory gene-associated enhancer in macrophages after LPS stimulation.

Figure 6.

(A) Proximity of chromatin regions altered by LA in BMDMs stimulated with LPS to transcription start sites (TSSs).

(B) Enrichment analysis of chromatin regions altered by LA for enhancers using public chromatin immunoprecipitation sequencing (ChIP-seq) data (ChIP-Atlas).

(C) ChIP-qPCR analysis of H3K27 acetylation (right) in pro-inflammatory gene-associated ATAC-seq regions closed with LA (left). Data in (C) are mean ± SD of triplicates. Student’s t test (unpaired): *p < 0.05, **p < 0.001, ***p < 0.001.