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. 2024 Mar 14;2024:5341646. doi: 10.1155/2024/5341646

Table 2.

Association between Hb1Ac (%) and SUA (μmol/L).

Exposure Model 1 Model 2 Model 3
β (95% CI) P value β (95% CI) P value β (95% CI) P value
Hb1Ac (%) 2.89 (1.19, 4.60) 0.0009 −0.82 (−2.44, 0.80) 0.3196 −7.93 (−9.49, −6.37) <0.0001
Glycosylated hemoglobin categories
 Q1 (2.8–5.2) −29.20 (−49.64, −8.75) 0.0052 −16.77 (−34.34, 0.80) 0.0616 −14.82 (−31.13, 1.49) 0.0752
 Q2 (5.2–5.5) 0.68 (−44.42, 45.79) 0.9763 −10.17 (−49.55, 29.21) 0.6128 −23.59 (−59.29, 12.11) 0.1954
 Q3 (5.5–5.9) 25.63 (−5.31, 56.56) 0.1046 27.15 (−1.35, 55.66) 0.0620 3.38 (−23.20, 29.96) 0.8031
 Q4 (5.9–17) −9.87 (−12.33, −7.42) <0.0001 −9.42 (−11.79, −7.04) <0.0001 −11.79 (−14.08, −9.50) <0.0001
P for trend <0.0001 <0.0001 <0.0001
Subgroup analysis stratified by sex
 Male −3.07 (−5.17, −0.98) 0.0041 −3.75 (−5.94, −1.57) 0.0008 −10.38 (−12.51, −8.24) <0.0001
 Female 7.43 (5.12, 9.74) <0.0001 2.76 (0.40, 5.13) 0.0219 −5.06 (−7.31, −2.81) <0.0001
Subgroup analysis stratified by age
 ≥20, <40 3.54 (−0.55, 7.63) 0.0897 2.46 (−0.96, 5.88) 0.1581 −6.55 (−9.81, −3.29) <0.0001
 ≥40, <60 −1.55 (−4.11, 1.01) 0.2355 −3.03 (−5.37, −0.69) 0.0112 −9.44 (−11.68, −7.20) <0.0001
 ≥60, <80 2.26 (−0.93, 5.44) 0.1650 1.51 (−1.56, 4.58) 0.3349 −6.77 (−9.84, −3.71) <0.0001
 ≥80 2.84 (−7.80, 13.47) 0.6013 1.71 (−9.07, 12.49) 0.7565 −4.79 (−15.98, 6.40) 0.4018
Subgroup analysis stratified by race
 Mexican American −2.23 (−6.34, 1.88) 0.2884 −5.63 (−9.45, −1.80) 0.0040 −10.58 (−14.24, −6.91) <0.0001
 Other Hispanic 0.65 (−4.17, 5.47) 0.7912 −3.01 (−7.46, 1.44) 0.1850 −11.04 (−15.61, −6.47) <0.0001
 Non-Hispanic White 7.19 (3.94, 10.43) <0.0001 2.05 (−1.06, 5.17) 0.1970 −9.38 (−12.39, −6.36) <0.0001
 Non-Hispanic Black 2.99 (−0.13, 6.12) 0.0604 −0.41 (−3.30, 2.47) 0.7780 −5.95 (−8.70, −3.20) <0.0001
 Other race/ethnicity 2.94 (−2.28, 8.16) 0.2705 0.54 (−4.43, 5.51) 0.8312 −6.67 (−11.64, −1.69) 0.0088

Model 1: no covariates were adjusted. Model 2: age, sex, and race were adjusted. Model 3: age, sex, race/ethnicity, education level, the ratio of family income to poverty, BMI, energy intake, protein intake, carbohydrate intake, dietary fiber intake, total fat intake, LDL-C, HDL-C, TG, TCHO, urine albumin, urine creatinine, albumin, creatinine ratio, SBP, DBP, heavy alcohol consumption, smoking status, and minutes sedentary activity were adjusted. In the subgroup analysis stratified by sex, age, and race/ethnicity, the model was not adjusted for sex, age, and race/ethnicity, respectively.