TABLE 3.
CTL activities against various proteins of HIV-1LAI
| Target antigen | LUa for donor:
|
||||||
|---|---|---|---|---|---|---|---|
| B12 | B15 | B16 | B18 | B20 | B22 | W121 | |
| Env/LAI | <3 | <3 | <3 | 80 | <3 | <3 | <3 |
| Gp120 | <3 | <3 | NT | 37 | NT | <3 | <3 |
| Gp41 | <3 | <3 | NT | 28 | NT | <3 | <3 |
| Gag/LAI | <3 | 27 | 65 | 58 | 64 | 42 | 130 |
| P24 | NT | 14 | <3 | 12 | <3 | 33 | 110 |
| P18 | NT | 19 | <3 | 35 | 51 | <3 | 68 |
| Pol/LAI | 79 | 32 | 143 | 28 | 36 | 52 | 17 |
| RT | 60 | <3 | <3 | 43 | <3 | <3 | <3 |
| Int | 43 | 41 | 179 | 56 | 18 | 37 | 26 |
| Pro | <3 | <3 | <3 | <3 | 12 | <3 | <3 |
| Nef/LAI | 47 | <3 | 234 | 93 | <3 | 63 | 23 |
| Nef-1 | <3 | <3 | NT | <3 | <3 | <3 | <3 |
| Nef-2 | 38 | <3 | 56 | 82 | <3 | 82 | 42 |
| Nef-3 | <3 | <3 | NT | <3 | <3 | <3 | <3 |
a
LU were calculated as described in Materials and Methods. NT, not tested.