Skip to main content
. 2024 Feb 19;30(3):699–707. doi: 10.1038/s41591-024-02824-y

Extended Data Fig. 8. TMEM176A/B expression and expression levels of genes related to the NLRP3 inflammasome in monocytes upon regorafenib-nivolumab treatment.

Extended Data Fig. 8

a, UMAP plots showing normalized expressions of TMEM176A and TMEM176B in PBMCs. b, Violin plots showing the average expression of the TMEM176A and TMEM176B genes before and after treatment among long-term responders (LR; n = 15) and early progressors (EP; n = 13). c, Violin plots showing the module score for the gene set related to the NLRP3 inflammasome signaling pathway in each monocyte subcluster in LR (n = 9) and EP (n = 9). *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001, according to a two-sided Wilcoxon signed-rank test for paired groups.