TABLE 1.
Functional classification | Single-cell ATAC-seq markers | Single-cell RNA-Seq markers | References |
---|---|---|---|
Mechano-Fibrotic | Col1a1, Acta2, Pdgfra, Ptk2 | Pdgfr-a, Ptk2, Tgfb2, Chd2, Coll1a1, Coll1a2, Mest, Plac8, Col3a1, Col5a1 Timp1, Timp2, Mmp3 | Foster et al. (2021), Phan et al. (2021), Phan et al. (2020) |
Activated-Responder | Thbs1, Thbs2 | Fn1, Thbs1 | Foster et al. (2021) |
Remodeling-Proliferator | Jak1, Jak2, Jak3, Ptk2b | Cxcl2, Spp1, Crabp1 | Foster et al., 2021, Phan et al. (2021) |