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. 2024 Mar 21;14:6777. doi: 10.1038/s41598-024-56845-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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dECM_DPSCs regulated mineralization potency of GSCs via Hippo and Wnt signaling pathways. (a) Mineralization capacity of reseeded GSCs was determined using ARS and Von Kossa stainings. (b) Relative ARS quantification was demonstrated. (c) Effects of inhibitors of several signaling pathways were evaluated using ARS staining. Scale bars: 300 µm. (d) Relative ARS quantification of reseeded GSCs comparing between N- and OM-dECM_DPSCs that were cultured in growth medium. (e) Relative ARS quantification of reseeded GSCs comparing between N- and OM-dECM_DPSCs that were cultured in osteogenic induction medium.