Table 2.

Proposal for a list of allowed flavourings in e-cigarette e-liquids

CAS No	Flavouring name	Flavour description	Association with tobacco
35044-68-9	beta-Damascone	Complex odour of blackcurrant, plum, rose, honey and tobacco	Tobacco-like flavour
23726-91-2	(E)-beta-Damascone	Complex odour of blackcurrant, plum, rose, honey and tobacco	Tobacco-like flavour
23726-92-3	(Z)-beta-Damascone	Complex odour of blackcurrant, plum, rose, honey and tobacco	Tobacco-like flavour
23696-85-7	Damascenone	Fruity floral with apple-plum-raisin-prune, tea, rose, tobacco notes	Tobacco-like flavour
23726-93-4	(E)-beta-Damascenone	Fruity floral with apple-plum-raisin-prune, tea, rose, tobacco notes	Tobacco-like flavour
1125-21-9	Ketoisophorone	Tobacco-like, hay straw, tea notes, honey	Tobacco-like flavour
4883-60-7	2-Hydroxy-3,5,5-trimethyl-2-cyclohexenone	Sweet, musty tea, caramellic odour; musty, tea, nutty, tobacco taste	Tobacco-like flavour
536-78-7	3-Ethylpyridine	Strong tobacco, roasted, nutty, smoky notes odour; tobacco-like flavour	Tobacco-like flavour
350-03-8	3-Acetylpyridine	Strong, burnt roasted, nutty, cigar tobacco-like	Tobacco-like flavour
91-10-1	2,6-Dimethoxyphenol	Phenolic-woody-medicinal, smoky odour; a tarry, spicy, smoky (bacon) taste	Attribute of tobacco aroma
67-47-0	5-(Hydroxymethyl)-2-furfural	Herbaceous winey hay-like odour, sweet herbaceous hay and tobacco-like taste	Tobacco-like flavour
591-12-8	alpha-Angelica lactone	Sweet, bread, molasses, coumarin, tobacco odour; nut-like taste	Tobacco-like flavour
503-74-2	Isovaleric acid	Very sour, ’sweaty’, cheesy, odour; fruity on dilution	Attribute of tobacco aroma
1139-30-6	(−)-Caryophyllene oxide	Dry, woody, faint cedar, tobacco-like notes	Tobacco-like flavour
3738-00-9	Ambroxide	Intense velvety ambergris notes	Present in tobacco smoke
564-20-5	(3aR)-(+)-Sclareolide	Cedary; impact compound of certain tobaccos; fish and berry flavour improver	Tobacco-like flavour

Terms associated with tobacco or tobacco smoke are indicated in bold.