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Response to SSRD in IBS-D patients, stratified according to SI hypomorphic genotype (double-carrier, single-carrier and non-carrier groups), at 2 weeks (top) and 4 weeks (bottom). *p=0.043 for double-carriers versus other groups (one-tailed Fisher’s exact test). IBS-D, irritable bowel syndrome-diarrhoea; SI, sucrase-isomaltase; SSRD, sucrose and starch-restricted diet.
