FIG. 4.

Locations of the deletions present within the nef gene in PBMC derived from patient SG1 in June 1996. A schematic drawing of the genomic structure of the NL4-3 HIV-1 clone (1) for the same region is shown at the top. The positions of the nested-PCR primers are indicated by arrows. Black boxes represent normal sequence, while blank spaces represent deletions. Nucleotide numbering refers to NL4-3 sequence positions. The numbers above the blank regions represent the sizes of the deletions. The deletions shown in the LD row are referred to the sequencing of the LD-PCR product.