Table 2.
Univariate and multivariable analyses of factors associated with willingness to receive the EV-71 vaccine (N = 3,626).
| Univariate analysis | Multivariate logistic regression† | ||||||
|---|---|---|---|---|---|---|---|
| N (%) | Extremely willing (N = 1,047) | Somewhat willing/Somewhat unwilling/Extremely unwilling (N = 2,579) | OR (95%CI) | value of p | Extremely willing vs. Somewhat willing/Somewhat unwilling/Extremely unwilling OR (95%CI) | value of p | |
| Social demographic characteristics | |||||||
| Guardian factor | |||||||
| Age (years) | |||||||
| <30 | 1,049 (28.9) | 366 (34.9) | 683 (65.1) | 2.05 (1.58–2.67) | <0.001 | 1.11 (0.77–1.60) | 0.579 |
| 30–40 | 2,133 (58.8) | 589 (27.6) | 1,544 (72.4) | 1.46 (1.14–1.87) | 0.87 (0.62–1.23) | 0.435 | |
| >40 | 444 (12.3) | 92 (20.7) | 352 (79.3) | Reference | Reference | ||
| Relationship | |||||||
| Father | 875 (24.1) | 242 (27.7) | 633 (72.3) | 1.94 (1.28–2.93) | <0.001 | 1.36 (0.79–2.34) | 0.273 |
| Mother | 2,563 (70.7) | 774 (30.2) | 1,789 (69.8) | 2.19 (1.48–3.25) | 1.57 (0.92–2.68) | 0.101 | |
| Other guardians | 188 (5.2) | 31 (16.5) | 157 (83.5) | Reference | Reference | ||
| Birthplace | |||||||
| Urban | 1,208 (33.3) | 378 (31.3) | 830 (68.7) | 1.19 (1.02–1.38) | 0.023 | 0.96 (0.79–1.17) | 0.670 |
| Rural | 2,418 (66.7) | 669 (27.7) | 1,749 (72.3) | Reference | Reference | ||
| Workplace | |||||||
| Urban | 2,236 (61.7) | 692 (3 0.9) | 1,544 (69.1) | 1.31 (1.12–1.52) | <0.001 | 0.89 (0.72–1.09) | 0.251 |
| Rural | 1,390 (38.3) | 355 (25.5) | 1,035 (74.5) | Reference | Reference | ||
| Census register place | |||||||
| Fujian Province | 3,361 (92.7) | 954 (28.4) | 2,407 (71.6) | Reference | 0.020 | Reference | |
| Other provinces | 265 (7.3) | 93 (35.1) | 172 (64.9) | 1.36 (1.05–1.78) | 0.79 (0.58–1.09) | 0.147 | |
| Occupation | |||||||
| Professionals and managerial | 911 (25.1) | 313 (34.4) | 598 (65.6) | 1.61 (1.28–2.01) | <0.001 | 1.17 (0.87–1.57) | 0.290 |
| Clerks | 237 (6.5) | 86 (36.3) | 151 (63.7) | 1.75 (1.27–2.40) | 1.21 (0.82–1.79) | 0.332 | |
| Industrial workers | 318 (8.8) | 69 (21.7) | 249 (78.3) | 0.85 (0.61–1.17) | 0.96 (0.66–1.40) | 0.820 | |
| Self-employed | 411 (11.3) | 142 (34.5) | 269 (65.5) | 1.62 (1.24–2.12) | 1.54 (1.11–2.14) | 0.010 | |
| Farmers | 431 (11.9) | 80 (18.6) | 351 (81.4) | 0.70 (0.52–0.94) | 0.95 (0.66–1.36) | 0.767 | |
| Service personnel | 164 (4.5) | 46 (28.0) | 118 (72.0) | 1.20 (0.82–1.76) | 1.16 (0.75–1.82) | 0.505 | |
| Others occupation | 491 (13.5) | 148 (30.1) | 343 (69.9) | 1.32 (1.02–1.72) | 1.24 (0.91–1.69) | 0.170 | |
| Housewife/Retiree/unemployed | 663 (18.3) | 163 (24.6) | 500 (75.4) | Reference | Reference | ||
| Highest education level | |||||||
| High school and below | 1,845 (50.9) | 429 (23.3) | 1,416 (76.7) | Reference | <0.001 | Reference | |
| University and above | 1,781 (49.1) | 618 (34.7) | 1,163 (65.3) | 1.75 (1.52–2.03) | 1.31 (1.07–1.61) | 0.020 | |
| Average annual household income (CNY¥) | |||||||
| <4,000 | 1,071 (29.5) | 233 (21.8) | 838 (78.2) | Reference | <0.001 | Reference | |
| 4,000–7,999 | 1,436 (39.6) | 425 (29.6) | 1,011 (70.4) | 1.41 (1.01–1.97) | 1.26 (0.86–1.85) | 0.238 | |
| 8,000–15,999 | 953 (26.3) | 320 (33.6) | 633 (66.4) | 1.69 (1.22–2.35) | 1.33 (0.91–1.96) | 0.146 | |
| ≥16,000 | 166 (4.6) | 69 (41.6) | 97 (58.4) | 2.55 (1.82–3.60) | 1.62 (1.07–2.44) | 0.023 | |
| Number of children aged 0–5 years in the family | |||||||
| 1 | 2,916 (80.4) | 844 (28.9) | 2,072 (71.1) | 1.01 (0.85–1.22) | 0.853 | ||
| >1 | 710 (19.6) | 203 (28.6) | 507 (71.4) | Reference | |||
| Knowledge score of HFMD | |||||||
| High (12–14) | 1,765 (48.7) | 686 (38.9) | 1,079 (61.1) | 2.64 (2.28–3.07) | <0.001 | 1.90 (1.57–2.29) | |
| Low (0–11) | 1,861 (51.3) | 361 (19.4) | 1,500 (80.6) | Reference | Reference | <0.001 | |
| Children’s factor | |||||||
| Child’s gender | |||||||
| Boy | 2,057 (56.7) | 571 (27.8) | 1,486 (72.2) | Reference | 0.090 | ||
| Girl | 1,569 (43.3) | 476 (30.3) | 1,093 (69.7) | 0.88 (0.76–1.02) | |||
| Child’s age (years) | |||||||
| <3 | 2,089 (57.6) | 728 (34.8) | 1,361 (65.2) | 2.04 (1.75–2.38) | <0.001 | 1.65 (1.33–2.03) | <0.001 |
| 3–5 | 1,537 (42.4) | 319 (20.8) | 1,218 (79.2) | Reference | Reference | ||
| Child’s physical condition | |||||||
| Healthy | 3,348 (92.3) | 989 (29.5) | 2,359 (70.5) | 1.59 (1.18–2.14) | 0.002 | 1.13 (0.81–1.58) | 0.480 |
| Frequently sick | 278 (7.7) | 58 (20.9) | 220 (79.1) | Reference | Reference | ||
| Child’s category | |||||||
| Nursery children | 1,741 (48.0) | 435 (25.0) | 1,306 (75.0) | Reference | <0.001 | Reference | |
| Non-nursery children | 1,885 (52.0) | 612 (32.5) | 1,273 (67.5) | 1.44 (1.25–1.67) | 0.91 (0.75–1.11) | 0.366 | |
| Child’s HFMD history | |||||||
| Yes | 314 (8.7) | 81 (25.8) | 233 (74.2) | Reference | 0.208 | ||
| No | 3,312 (91.3) | 966 (29.2) | 2,346 (70.8) | 1.18 (0.91–1.54) | |||
| Other children around who have suffered from HFMD | |||||||
| Yes | 1,133 (31.2) | 339 (29.9) | 794 (70.1) | 1.08 (0.92–1.26) | 0.349 | ||
| No/unsure | 2,493 (68.8) | 708 (28.4) | 1,785 (71.6) | Reference | |||
| Health belief | |||||||
| Perceived susceptibility | |||||||
| My child has a high chance of getting HFMD | |||||||
| Yes | 1,648 (45.4) | 574 (34.8) | 1,074 (65.2) | 1.70 (1.47–1.97) | <0.001 | 1.25 (1.02–1.52) | 0.030 |
| No | 1,978 (54.6) | 473 (23.9) | 1,505 (76.1) | Reference | Reference | ||
| Worry about my child getting HFMD | |||||||
| Yes | 2,997 (82.7) | 955 (31.9) | 2,042 (68.1) | 2.73 (2.16–3.45) | <0.001 | 1.79 (1.34–2.37) | <0.001 |
| No | 629 (17.3) | 92 (14.6) | 537 (85.4) | Reference | Reference | ||
| Perceived severity | |||||||
| My child will be very sick if they get HFMD | |||||||
| Yes | 1,842 (50.8) | 632 (34.3) | 1,210 (65.7) | 1.72 (1.49–1.99) | <0.001 | 1.45 (1.19–1.76) | <0.001 |
| No | 1,784 (49.2) | 415 (23.3) | 1,369 (76.7) | Reference | Reference | ||
| HFMD infection can affect my child’s schooling | |||||||
| Yes | 3,261 (89.9) | 983 (30.1) | 2,278 (69.9) | 2.03 (1.53–2.69) | <0.001 | 1.07 (0.76–1.51) | 0.700 |
| No | 365 (10.1) | 64 (17.5) | 301 (82.5) | Reference | Reference | ||
| Perceived benefits | |||||||
| HFMD can be prevented | |||||||
| Yes | 3,385 (93.4) | 1,022 (30.2) | 2,363 (69.8) | 3.74 (2.45–5.69) | <0.001 | 1.01 (0.56–1.82) | 0.975 |
| No | 241 (6.6) | 25 (10.4) | 216 (89.6) | Reference | Reference | ||
| EV-71 Vaccination is effective in preventing HFMD | |||||||
| Yes | 3,313 (91.4) | 1,025 (30.9) | 2,288 (69.1) | 5.93 (3.82–9.20) | <0.001 | 2.73 (1.52–4.90) | <0.001 |
| No | 313 (8.6) | 22 (7.0) | 291 (93.0) | Reference | Reference | ||
| Perceived barriers | |||||||
| I do not have time to take my child to get the EV-71 vaccine | |||||||
| Yes | 986 (27.2) | 203 (20.6) | 783 (79.4) | Reference | <0.001 | Reference | |
| No | 2,640 (72.8) | 844 (32.0) | 1,796 (68.0) | 1.81 (1.52–2.16) | 1.39 (1.12–1.71) | 0.002 | |
| Worry about the side effects | |||||||
| Yes | 1,985 (54.7) | 396 (19.9) | 1,589 (80.1) | Reference | <0.001 | Reference | |
| No | 1,641 (45.3) | 651 (39.7) | 990 (60.3) | 2.64 (2.28–3.06) | 1.56 (1.23–1.97) | <0.001 | |
| Concern about the safety of the EV-71 vaccine | |||||||
| Yes | 1,920 (53.0) | 367 (19.1) | 1,553 (80.9) | Reference | <0.001 | Reference | |
| No | 1,706 (47.0) | 680 (39.9) | 1,026 (60.1) | 2.81 (2.42–3.26) | 1.65 (1.30–2.08) | <0.001 | |
| EV-71 vaccine is expensive | |||||||
| Yes | 1,960 (54.1) | 324 (16.5) | 1,636 (83.5) | Reference | <0.001 | Reference | |
| No | 1,666 (45.9) | 723 (43.4) | 943 (56.6) | 3.87 (3.32–4.51) | 2.94 (2.45–3.53) | <0.001 | |
| Cues to action | |||||||
| I often get information from health education program about EV-71 vaccination | |||||||
| Yes | 2,246 (61.9) | 757 (33.7) | 1,489 (66.3) | 1.91 (1.63–2.23) | <0.001 | 1.21 (0.99–1.50) | 0.069 |
| No | 1,380 (38.1) | 290 (21.0) | 1,090 (79.0) | Reference | Reference | ||
| Medical staff recommended that I shall get my child vaccinated with EV-71 vaccine | |||||||
| Yes | 2,690 (74.2) | 887 (33.0) | 1,803 (67.0) | 2.39 (1.98–2.88) | <0.001 | 1.77 (1.40–2.24) | <0.001 |
| No | 936 (25.8) | 160 (17.1) | 776 (82.9) | Reference | Reference | ||
†
Hosmer–Lemeshow test, chi-square: 6.011, value of p: 0.646; Nagelkerke R2: 0.287.