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. 2024 Mar 7;12:1336687. doi: 10.3389/fpubh.2024.1336687

Table 3.

Multinomial logic regression of factors associated with marginal willingness-to-pay (WTP) for EV-71 vaccine (N = 3,626).

Univariate analysis Multivariate logistic regression
Marginal WTP Marginal WTP
CNY¥100/200 (N = 2,221) CNY¥300/400 (N = 662) ≥CNY¥500 (N = 743) p-value CNY¥300/400 OR (95% CI) p-value ≥CNY¥500 OR (95% CI) p-value
Social demographic characteristics
Guardian factor
Age (years)
<30 575 (54.8) 207 (19.7) 267 (25.5) <0.001 1.17 (0.79–1.73) 0.432 1.57 (1.00–2.47) 0.049
30–40 1,343 (63.0) 370 (17.3) 420 (19.7) 0.97 (0.68–1.39) 0.862 1.12 (0.74–1.72) 0.587
>40 303 (68.2) 85 (19.1) 56 (12.6) Reference Reference
Relationship
Father 505 (57.7) 162 (18.5) 208 (23.8) <0.001 0.74 (0.44–1.25) 0.262 0.97 (0.49–1.90) 0.919
Mother 1,589 (62.0) 459 (17.9) 515 (20.1) 0.67 (0.40–1.11) 0.122 0.71 (0.36–1.39) 0.317
Other guardians 127 (67.6) 41 (21.8) 20 (10.6) Reference Reference
Birthplace
Urban 674 (55.8) 238 (19.7) 296 (24.5) <0.001 1.06 (0.86–1.31) 0.595 1.05 (0.84–1.31) 0.687
Rural 1,547 (64.0) 424 (17.5) 447 (18.5) Reference Reference
Workplace
Urban 1,252 (56.0) 433 (19.4) 551 (24.6) <0.001 1.14 (0.91–1.43) 0.250 1.19 (0.93–1.53) 0.168
Rural 969 (69.7) 229 (16.5) 192 (13.8) Reference Reference
Census register place
Fujian Province 2,086 (62.1) 603 (17.9) 672 (20.0) 0.002 Reference Reference
Other provinces 135 (50.9) 59 (22.3) 71 (26.8) 1.46 (1.03–2.05) 0.033 1.52 (1.05–2.19) 0.025
Occupation
Professionals and managerial 514 (56.4) 179 (19.6) 218 (23.9) <0.001 1.04 (0.75–1.43) 0.820 1.08 (0.76–1.53) 0.676
Clerks 114 (48.1) 52 (21.9) 71 (30.0) 1.11 (0.72–1.72) 0.631 1.09 (0.70–1.53) 0.695
Industrial workers 213 (67.0) 48 (15.1) 57 (17.9) 0.74 (0.49–1.11) 0.142 1.09 (0.70–1.72) 0.604
Self-employed 236 (57.4) 73 (17.8) 102 (24.8) 0.87 (0.61–1.26) 0.465 1.13 (0.72–1.75) 0.482
Farmers 319 (74.0) 72 (16.7) 40 (9.3) 1.00 (0.69–1.45) 0.994 1.15 (0.78–1.70) 0.550
Service personnel 100 (61.0) 28 (17.1) 36 (22.0) 0.86 (0.53–1.42) 0.564 1.13 (0.67–1.90) 0.650
Others occupation 279 (56.8) 91 (18.5) 121 (24.6) 1.08 (0.77–1.50) 0.666 1.42 (0.99–2.04) 0.058
Housewife/ retiree/ unemployed 446 (67.3) 119 (17.9) 98 (14.8) Reference Reference
Highest education level
High school and below 1,242 (67.3) 327 (17.7) 276 (15.0) <0.001 Reference Reference
University and above 979 (55.0) 335 (18.8) 467 (26.2) 1.01 (0.80–1.28) 0.954 1.39 (1.09–1.76) 0.010
Average annual household income (CNY¥)
<4,000 829 (77.4) 144 (13.4) 98 (9.2) <0.001 Reference Reference
4,000–7,999 853 (59.4) 292 (20.3) 291 (20.3) 0.78 (0.48–1.27) 0.573 1.03 (0.68–1.57) 0.873
8,000–15,999 465 (48.8) 198 (16.9) 290 (30.4) 0.87 (0.54–1.40) 0.326 1.41 (0.93–2.14) 0.110
≥16,000 74 (44.6) 28 (16.9) 64 (38.6) 1.60 (0.96–2.66) 0.065 3.23 (2.02–5.15) <0.001
Number of children aged 0–5 in the family
1 1,759 (60.3) 537 (18.4) 620 (21.3) 0.034 1.15 (0.91–1.45) 0.254 1.45 (1.12–1.88) 0.004
>1 462 (65.1) 125 (17.6) 123 (17.3) Reference Reference
Knowledge score of HFMD
High (12–14) 1,060 (60.1) 338 (19.2) 367 (20.8) 0.293
Low (0–11) 1,161 (62.4) 324 (17.4) 376 (20.2)
Children’s factor
Child’s gender
Boy 1,249 (60.7) 389 (18.9) 419 (20.4) 0.504
Girl 972 (62.0) 273 (17.4) 324 (20.7)
Child’s age (years)
<3 1,182 (56.6) 397 (19.0) 510 (24.4) <0.001 1.09 (0.87–1.37) 0.474 1.66 (1.29–2.13) <0.001
3–5 1,039 (67.6) 265 (17.2) 233 (15.2) Reference Reference
Child’s physical condition
Healthy 2,045 (61.1) 613 (18.3) 690 (20.6) 0.749
Frequently sick 176 (63.3) 49 (17.6) 53 (19.1)
Child’s category
Nursery children 1,088 (62.5) 304 (17.5) 349 (20.0) 0.312
Non-nursery children 1,133 (60.1) 358 (19.0) 394 (20.9)
Child’s HFMD history
Yes 216 (68.8) 50 (15.9) 48 (15.3) 0.011 Reference Reference
No 2,005 (60.5) 612 (18.5) 695 (21.0) 1.25 (0.88–1.77) 0.217 1.16 (0.79–1.71) 0.458
Other children around who have suffered from HFMD
Yes 712 (62.8) 199 (17.6) 222 (19.6) 0.414
No/unsure 1,509 (60.5) 463 (18.6) 521 (20.9)
Health belief
Perceived susceptibility
My child has a high chance of getting HFMD
Yes 985 (59.8) 326 (19.8) 337 (20.4) 0.085
No 1,236 (62.5) 336 (17.0) 406 (20.5)
Worry about my child getting HFMD
Yes 1,781 (59.4) 558 (18.6) 658 (22.0) <0.001 1.37 (1.03–1.81) 0.032 1.82 (1.33–2.49) <0.001
No 440 (70.0) 104 (16.5) 85 (13.5) Reference Reference
Perceived severity
My child will be very sick if they get HFMD
Yes 1,092 (59.3) 358 (19.4) 392 (21.3) 0.042 1.16 (0.93–1.45) 0.181 1.06 (0.84–1.34) 0.607
No 1,129 (63.3) 304 (17.0) 351 (19.7) Reference Reference
HFMD infection can affect my child’s schooling
Yes 1,987 (60.9) 583 (17.9) 691 (21.2) 0.003 0.79 (0.56–1.10) 0.167 1.16 (0.77–1.75) 0.478
No 234 (64.1) 79 (21.6) 52 (14.2) Reference Reference
Perceived benefits
HFMD can be prevented
Yes 2,058 (60.8) 606 (17.9) 721 (21.3) <0.001 0.65 (0.41–1.03) 0.068 1.12 (0.59–2.12) 0.738
No 163 (67.6) 56 (23.2) 22 (9.1) Reference Reference
EV-71 vaccination is effective in preventing HFMD
Yes 1,996 (60.2) 600 (18.1) 717 (21.6) <0.001 1.15 (0.75–1.79) 0.521 2.09 (1.16–3.76) 0.014
No 225 (71.9) 62 (19.8) 26 (8.3) Reference Reference
Perceived barriers
I do not have time to take my child to get EV-71 vaccine
Yes 678 (68.8) 176 (17.8) 132 (13.4) <0.001 Reference Reference
No 1,543 (58.4) 486 (18.4) 611 (23.1) 1.05 (0.84–1.31) 0.687 1.26 (0.98–1.63) 0.073
Worry about the side effects
Yes 1,331 (67.1) 343 (17.3) 311 (15.7) <0.001 Reference Reference
No 890 (54.2) 319 (19.4) 432 (26.3) 0.90 (0.69–1.17) 0.422 1.07 (0.81–1.41) 0.653
Concern about the safety of the EV-71 vaccine
Yes 1,313 (68.4) 316 (16.5) 291 (15.2) <0.001 Reference Reference
No 908 (53.2) 346 (20.3) 452 (26.5) 1.25 (0.97–1.63) 0.090 1.09 (0.82–1.44) 0.560
EV-71 vaccine is expensive
Yes 1,550 (79.1) 299 (15.3) 111 (5.7) <0.001 Reference Reference
No 671 (40.3) 363 (21.8) 632 (37.9) 2.58 (2.11–3.17) <0.001 10.86 (8.49–13.88) <0.001
Cues to action
I often get information from health education program about EV-71 vaccination
Yes 1,366 (60.8) 409 (18.2) 471 (21.0) 0.653
No 855 (62.0) 253 (18.3) 272 (19.7)
Medical staff recommended that I shall get my child vaccinated with EV-71 vaccine
Yes 1,627 (60.5) 509 (18.9) 554 (20.6) 0.162
No 594 (63.5) 153 (16.3) 189 (20.2)

Multinomial regression; reference group: CNY¥100/200.

Goodness of fit; Pearson’s chi-square: 7386.496, p-value: 0.002; Nagelkerke R2: 0.300.