Fig. 1.

Overall information of the bladder microbiota culture collection. A–D Distribution of genome assembly, completeness, contamination, coverage (on a log10 scale), and L50 values, respectively. E Phylogenomic tree of the 196 bacterial species (assigned by GTDB) represented in the bladder genome collection. A single genome per species was selected out of the 1134 high-quality isolated genomes (> 90% completeness, < 5% contamination) to reconstruct the multiple sequence alignment of 71 core bacterial genes. Bacterial species are colored by phylum. *The bacterial species only found in males. F The diversity of isolated genomes was compared with the total diversity observed in the 16S sequence data (as shown in genus level) obtained from 392 bladder urine samples