Table 2.
General clinical characteristics of the patients
| Variables | IT(n=46) | IA(n=50) | LR(n=20) | RA(n=21) | HC(n=32) | P value |
|---|---|---|---|---|---|---|
| Male, n (%) | 22(47.83) | 37(74.00) | 9(45.00) | 13(61.90) | 18(56.25) | 0.067 c |
| Age (years) | 35(31-46) | 39(34-49) | 40(31-55) | 44(36-49) | 48(32-58) | 0.053 b |
| HbsAg(IU/ml) | 33725.95(6390.21-54364.65) | 10819.65(4075.77-21753.43) | 3679.90(1095.77-7375.08) | 3050.29(1684.47-8662.55) | NA | <0.001 b |
| HBeAg(IU/ml) | 1394.59(541.24-1588.91) | 880.70(262.23-1436.98) | NA | NA | NA | <0.001 a |
| log10[HBV-DNA] | 7.97(5.25-8.40) | 6.92(5.49-8.06) | 3.45(3.08-3.96) | 4.79(3.47-5.81) | NA | <0.001 b |
| ALT(U/L) | 27.50(17.75-35.00) | 103.00(66.25-225.50) | 20.00(15.00-27.75) | 74.00(25.50-154.50) | 15.50(11.50-23.50) | <0.001 b |
| AST(U/L) | 21.50(18.00-27.25) | 65.00(44.75-114.25) | 20.00(18.00-24.75) | 41.00(22.50-99.50) | 19.00(15.50-22.00) | <0.001 b |
| AKP(U/L) | 77.00(61.75-94.25) | 90.50(76.00-104.50) | 75.50(62.75-97.50) | 88.00(66.50-98.00) | 74.50(57.50-84.00) | 0.029 b |
| GGT(U/L) | 19.00(12.00-31.00) | 38.50(27.25-94.50) | 16.50(12.25-25.25) | 30.00(19.50-61.50) | 21.00(13.25-27.75) | <0.001 b |
| TBIL(µmol/L) | 9.45(7.50-14.10) | 13.70(9.30-16.98) | 10.45(8.03-14.33) | 12.30(9.15-18.10) | 9.70(8.15-14.33) | 0.007 b |
| ALB(g/L) | 46.25(44.20-48.83) | 45.60(43.15-48.83) | 47.80(46.10-49.93) | 48.20(45.45-50.30) | 47.15(46.05-49.03) | 0.064 b |
| Cr(µmol/L) | 72.00(54.00-79.00) | 69.00(60.00-76.50) | 65.00(57.00-78.00) | 71.50(56.25-78.75) | 69.50(64.25-79.00) | 0.903 b |
| PLT(10^9/L) | 218.00(182.75-252.00) | 192.50(154.25-232.25) | 220.00(183.75-235.00) | 185.00(151.50-224.00) | 228.50(200.25-272.75) | 0.005 b |
| PTA(%) | 119.00(109.00-122.75) | 103.50(88.50-107.75) | 115.00(110.50-122.00) | 102.00(92.00-109.00) | 110.00(103.00-119.00) | 0.007 b |
| INR | 0.90(0.89-0.95) | 0.98(0.96-1.08) | 0.92(0.89-0.94) | 0.99(0.95-1.06) | 0.94(0.90-0.98) | <0.001 b |
| AFP(ng/ml) | 2.41(1.81-3.60) | 5.68(2.83-15.89) | 2.06(1.48-3.16) | 2.82(1.92-4.50) | 2.90(2.46-4.75) | <0.001 b |
Quantitative variables were expressed as medians (25th, 75th percentage)
Qualitative variables were expressed as number (percentage)
a Mann–Whitney U test. b Kruskal–Wallis H test. c chi-square test