Figure 1. Patient-reported outcome measurements (PROMs) in PwPMS with and without restro- and prospective evidence of disability progression.
BDI-II, Beck Depression Inventory-II; MSISphysical -29, Multiple Sclerosis Impact Scale-29, physical component; MSISpsychological -29, Multiple Sclerosis Impact Scale, psychological component; FSMC, fatigue score for motor and cognition. EDP: evidence of disability progression (retrospective, CDP: confirmed disability progression (prospective). P-value from linear regression models for EDP and mixed linear models for CDP as defined in the statistical analysis section. The boxplots are overlaid with individual measurements. Higher scores represent worse performance.