Table 2.
Adjusted regression coefficients (S.E.) for differences in lipid profile relative to a one-unit increase in log10-transformed diphenyl phosphate (DPhP), with results weighted for sampling strategy.
| Triglycerides (mg/dL) | Total Cholesterol (mg/dL) | Direct HDL-Cholesterol (mg/dL) | LDL-cholesterol (mg/dL) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Unweighted no./Population size | Regression coefficient (S.E.) | p | Unweighted no./Population size | Regression coefficient (S.E.) | p | Unweighted no./Population size | Regression coefficient (S.E.) | p | Unweighted no./Population size | Regression coefficient (S.E.) | p | |
| Overall | 1561/220622320 | 0.843 (4.344) | 0.849 | 1,406/ 203,187,852 | −5.775 (2.289) | 0.023 | 1,498 / 213,972,792 | −2.292 (0.802) | 0.012 | 731/105236024 | −4.500 (2.748) | 0.122 |
| Sex | ||||||||||||
| Male | 755/ 106,819,732 | 16.122 (10.981) | 0.163 | 681/ 98,729,779 | −0.237 (5.773) | 0.968 | 719/ 102,840,733 | −1.981 (1.003) | 0.067 | 333/ 48,901,316 | −0.124 (6.161) | 0.984 |
| Female | 806/ 113,802,587 | −10.299 (5.012) | 0.058 | 725 /104458072 | −9.552 (3.506) | 0.016 | 779/ 111,132,059 | −2.411 (1.067) | 0.039 | 398/ 56,334,708 | −6.912 (4.445) | 0.141 |
| Age (years) | ||||||||||||
| 20–50 | 839/ 124,784,683 | 12.725 (7.605) | 0.115 | 735/ 112,216,180 | −8.272 (4.171) | 0.066 | 807/ 120,910,742 | −3.361 (1.263) | 0.018 | 387/ 58,157,597 | −4.594 (3.260) | 0.179 |
| >50 | 722/ 95,837,636 | −9.246 (6.544) | 0.178 | 671/ 90,971,672 | −0.430 (4.665) | 0.928 | 691/ 93,062,050 | −0.891 (1.141) | 0.447 | 344/ 47,078,426 | −4.861 (4.073) | 0.251 |
| Body mass index (kg/m2) | ||||||||||||
| <25 | 467/ 65,076,848 | −1.659 (5.683) | 0.774 | 418/ 59,751,477 | −8.133 (3.634) | 0.041 | 450/ 62,953,107 | −3.372 (1.778) | 0.077 | 211/ 29,862,967 | −2.645 (4.805) | 0.59 |
| 25–30 | 508/ 70,207,421 | 3.103 (11.369) | 0.789 | 454/ 64,078,159 | −7.210 (3.845) | 0.08 | 483/ 67,990,603 | −2.717 (1.919) | 0.177 | 251/ 36,070,736 | −4.292 (5.664) | 0.46 |
| ≧30 | 586/ 85,338,049 | −0.037 (6.505) | 0.995 | 534/ 79,358,214 | −3.301 (6.074) | 0.595 | 565/ 83,029,082 | −1.152 (1.244) | 0.369 | 265/ 38,950,494 | −7.275 (5.472) | 0.204 |
| Smoking status | ||||||||||||
| Non-smoker | 371/ 53,265,487 | −2.750 (9.917) | 0.785 | 347/ 51,129,953 | −3.583 (9.139) | 0.701 | 362/ 52,515,709 | −1.266 (1.289) | 0.342 | 174/ 25,693,514 | 0.600 (8.855) | 0.947 |
| Current smoker (reference) | 323/ 42,288,856 | 13.000 (17.924) | 0.479 | 289/ 38,719,205 | −6.613 (5.262) | 0.228 | 313/ 41,401,542 | −1.304 (2.432) | 0.6 | 145/ 18,532,400 | −6.179 (6.065) | 0.324 |
| Alcohol consumption (drink/year) | ||||||||||||
| <12 | 1,048/ 157,895,769 | 4.311 (5.287) | 0.428 | 1,014/ 154,537,025 | −7.710 (3.571) | 0.047 | 1,014/ 154,537,025 | −2.794 (1.056) | 0.018 | 498/ 76,573,828 | −7.637 (4.077) | 0.081 |
| ≧12 | 415/ 50,927,354 | −10.455 (8.453) | 0.235 | 392/ 48,650,827 | −1.507 (4.479) | 0.741 | 392/ 48,650,827 | −1.023 (1.556) | 0.521 | 190/ 23,446,728 | 1.379 (3.500) | 0.7 |
| Income | ||||||||||||
| < 4,500 | 684/ 79,624,539 | −9.092 (9.695) | 0.363 | 645/ 75,642,861 | −7.352 (4.221) | 0.102 | 687/ 79,877,915 | −0.638 (1.018) | 0.54 | 331/ 38,366,303 | −7.679 (2.341) | 0.005 |
| ≧4,500 | 807/ 133,310,219 | 8.794 (9.612) | 0.375 | 761/ 127,544,990 | −4.528 (2.179) | 0.055 | 811/ 134,094,877 | −3.301 (0.914) | 0.003 | 372/ 64,320,395 | −1.818 (3.886) | 0.647 |
| Ethnicity | ||||||||||||
| Mexican-American | 213/ 19,744,438 | −7.864 (21.619) | 0.723 | 184/ 17,049,107 | −6.727 (5.359) | 0.238 | 193/ 18,020,950 | 0.844 (2.414) | 0.733 | 98/ 8,920,471 | −6.272 (6.096) | 0.338 |
| Other Hispanic | 141/ 13,089,856 | 42.381 (28.189) | 0.157 | 122/ 11,323,919 | 0.242 (9.151) | 0.979 | 130/ 12,232,075 | −0.779 (1.199) | 0.527 | 63/ 5,394,797 | −11.990 (10.227) | 0.279 |
| Non-Hispanic White | 707/ 145,840,898 | −4.860 (5.508) | 0.392 | 671/ 138,431,591 | −4.836 (2.718) | 0.095 | 694/ 143,134,248 | −2.630 (0.734) | 0.003 | 353/ 73,074,926 | −3.539 (3.627) | 0.345 |
| Non-Hispanic Black | 279/ 24,290,277 | 18.664 (9.565) | 0.073 | 246/ 21,266,181 | −6.655 (4.350) | 0.15 | 271/ 23,603,730 | −3.140 (1.941) | 0.13 | 119/ 10,150,633 | −12.266 (4.940) | 0.03 |
| Other Race – including Multi-Racial | 221/ 17,656,849 | 6.163 (11.926) | 0.613 | 183/ 15,117,052 | −11.975 (9.327) | 0.219 | 210/ 16,981,787 | −2.715 (2.577) | 0.309 | 98/ 7,695,195 | −1.614 (6.800) | 0.817 |
HDL, high-density lipoprotein; LDL, low-density lipoprotein; SE, standard error.