Table 4.
Adjusted regression coefficients (S.E.) for differences in TG, cholesterol, LDL, and HDL relative to a one-unit increase in log10-transformed biomarkers of bis-(1-chloro-2-propyl) phosphate (BCPP), with results weighted for sampling strategy.
| Triglycerides (mg/dL) | Total Cholesterol (mg/dL) | Direct HDL-Cholesterol (mg/dL) | LDL-cholesterol (mg/dL) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Unweighted no./Population size | Regression coefficient (S.E.) | p | Unweighted no./Population size | Regression coefficient (S.E.) | p | Unweighted no./Population size | Regression coefficient (S.E.) | p | Unweighted no./Population size | Regression coefficient (S.E.) | p | |
| Overall | 1564/221207358 | −10.195 (6.605) | 0.144 | 1,409 / 203,772,890 | −4.637 (2.019) | 0.036 | 1,501 / 214,557,830 | −1.302 (0.962) | 0.196 | 733 (105576082) | 0.938 (1.967) | 0.64 |
| Sex | ||||||||||||
| Male | 757/ 107,159,790 | −8.520 (10.973) | 0.45 | 683/99069837 | −0.424 (4.919) | 0.932 | 721/ 103,180,791 | −1.012 (1.057) | 0.354 | 335/ 49,241,374 | 2.420 (4.238) | 0.576 |
| Female | 807/ 114,047,567 | −13.286 (5.626) | 0.032 | 726/ 104,703,052 | −9.410 (3.448) | 0.016 | 780/ 111,377,039 | −1.376 (1.625) | 0.41 | 398/ 56,334,708 | −0.656 (3.449) | 0.852 |
| Age (years) | ||||||||||||
| 20–50 | 840/ 125,029,663 | −16.135 (8.700) | 0.083 | 736/ 112,461,159 | −5.568 (2.611) | 0.05 | 808/ 121,155,721 | −0.470 (1.320) | 0.727 | 387/ 58,157,597 | −2.797 (2.291) | 0.241 |
| >50 | 724/ 96,177,694 | 0.693 (10.362) | 0.948 | 673/ 91,311,730 | −1.835 (3.935) | 0.648 | 693/ 93,402,109 | −2.482 (1.594) | 0.14 | 346/ 47,418,484 | 6.926 (3.641) | 0.077 |
| Body mass index (kg/m2) | ||||||||||||
| < 25 | 468/ 65,321,828 | −9.355 (10.087) | 0.368 | 419/ 59,996,457 | −7.060 (4.152) | 0.11 | 451/ 63,198,087 | −1.049 (2.519) | 0.683 | 211/ 29,862,967 | 3.520 (4.175) | 0.412 |
| 25–30 | 509/ 70,510,125 | −27.472 (8.951) | 0.008 | 455/ 64,380,864 | −8.508 (5.872) | 0.168 | 484/ 68,293,307 | −2.064 (1.431) | 0.17 | 252/ 36,373,441 | −1.266 (4.764) | 0.794 |
| ≧30 | 587/ 85,375,403 | 4.860 (11.891) | 0.689 | 535/ 79,395,568 | −0.011 (5.288) | 0.998 | 566/ 83,066,435 | −0.696 (1.414) | 0.63 | 266/ 38,987,848 | 0.285 (6.649) | 0.966 |
| Smoking status | ||||||||||||
| Non-smoker | 373/ 53,547,820 | −17.431 (14.932) | 0.261 | 349/ 51,412,287 | −8.019 (5.211) | 0.145 | 364/ 52,798,042 | −0.164 (0.902) | 0.859 | 175/ 25,730,867 | −0.876 (5.645) | 0.879 |
| Secondhand smoke | ||||||||||||
| Current smoker | 323/ 42,288,856 | −6.269 (21.363) | 0.773 | 289/ 38,719,205 | −6.192 (5.965) | 0.316 | 313/ 41,401,542 | −1.888 (2.035) | 0.368 | 145/ 18,532,400 | 7.312 (4.860) | 0.153 |
| Alcohol consumption (drink/year) | ||||||||||||
| <12 | 1,050/ 158,178,103 | −8.849 (7.042) | 0.228 | 1,016/ 154,819,358 | −5.194 (1.931) | 0.017 | 1,016/ 154,819,358 | −1.578 (0.869) | 0.089 | 499/ 76,611,182 | −0.252 (2.138) | 0.908 |
| ≧12 | 416/ 51,230,058 | −18.495 (13.987) | 0.206 | 393/ 48,953,531 | −3.646 (5.984) | 0.551 | 393/ 48,953,531 | −1.006 (2.683) | 0.713 | 191/ 23,749,432 | 4.675 (7.369) | 0.537 |
| Income | ||||||||||||
| <4,500 | 685/ 79,661,893 | −11.414 (9.587) | 0.252 | 646/ 75,680,215 | −3.627 (3.708) | 0.344 | 688/ 79,915,269 | 0.566 (0.992) | 0.577 | 332/ 38,403,657 | 3.905 (4.846) | 0.433 |
| ≧4,500 | 809/ 133,857,903 | −10.892 (9.769) | 0.282 | 763/ 128,092,674 | −5.318 (2.414) | 0.044 | 813/ 134,642,561 | −2.233 (1.308) | 0.109 | 373/ 64,623,099 | −1.149 (2.369) | 0.635 |
| Ethnicity | ||||||||||||
| Mexican-American | 213/ 19,744,438 | −23.376 (13.074) | 0.101 | 184/ 17,049,107 | −7.905 (4.079) | 0.081 | 193/ 18,020,950 | 0.550 (1.708) | 0.753 | 98/ 8,920,471 | 10.110 (6.244) | 0.149 |
| Other Hispanic | 141/ 13,089,856 | 13.511 (36.005) | 0.714 | 122/ 11,323,919 | 4.941 (7.113) | 0.5 | 130/ 12,232,075 | −0.355 (2.522) | 0.89 | 63/ 5,394,797 | −0.973 (5.076) | 0.853 |
| Non-Hispanic White | 709/ 146,388,582 | −17.209 (8.371) | 0.058 | 673/ 138,979,276 | −8.009 (3.103) | 0.021 | 696/ 143,681,933 | −1.321 (1.368) | 0.35 | 354/ 73,377,630 | −0.541 (2.586) | 0.837 |
| Non-Hispanic Black | 280/ 24,327,630 | 16.231 (6.510) | 0.027 | 247/ 21,303,534 | 6.561 (5.413) | 0.247 | 272/ 23,641,084 | −1.621 (3.954) | 0.688 | 120/ 10,187,986 | −1.492 (5.812) | 0.802 |
| Other Race – including Multi-Racial | 221/ 17,656,849 | 13.031 (9.382) | 0.185 | 183/ 15,117,052 | 8.366 (6.667) | 0.229 | 210/ 16,981,787 | −2.657 (1.878) | 0.178 | 98/ 7,695,195 | 12.590 (6.103) | 0.064 |
HDL, high-density lipoprotein; LDL, low-density lipoprotein; SE, standard error.