Table 1.
Baseline Clinical and Laboratory Characteristics of the Study Patients According to the AEC Tertiles
| Variable | Tertile1 (AEC≤0.08) | Tertile2 (AEC 0.08–0.14) | Tertile3 (AEC>0.14) | P value |
|---|---|---|---|---|
| N=633 | N=537 | N=541 | ||
| Demographics | ||||
| Age (y) | 60.0±9.9 | 59.8±10.1 | 59.5±11.3 | 0.690 |
| Male sex, n (%) | 457(72.2) | 413(76.9) | 444(82.1) | <0.001 |
| BMI (kg/m2) | 25.3±3.0 | 25.7±2.9 | 26.2±3.3 | <0.001 |
| Medical measurements (on admission) | ||||
| SBP (mm Hg) | 130(120–140) | 130(120–140) | 130(120–140) | 0.194 |
| DBP (mm Hg) | 76(70–80) | 76(70–82) | 76(70–83) | 0.566 |
| Risk factors | ||||
| Current smoking, n (%) | 228(36.0) | 250(46.6) | 278(51.4) | <0.001 |
| Family history of CAD, n (%) | 208(32.7%) | 165(30.7%) | 174(32.1%) | 0.767 |
| Hypertension, n (%) | 397(62.7) | 337(62.8) | 354(65.4) | 0.559 |
| DM, n (%) | 285(45) | 243(45.3) | 259(47.9) | 0.569 |
| Dyslipidaemia, n (%) | 485(76.6) | 428(79.7) | 456(84.3) | 0.005 |
| Past PCI, n (%) | 208(32.9) | 165(30.7) | 174(32.2) | 0.733 |
| Previous MI, n (%) | 101(16.0) | 106(19.7) | 120(22.2) | 0.023 |
| Previous CVA, n (%) | 35(5.5) | 41(7.6) | 23(4.3) | 0.056 |
| PAD, n (%) | 61(9.6) | 52(9.7) | 63(11.6) | 0.453 |
| Cardiac failure, n (%) | 43(6.8) | 35(6.5) | 41(7.6) | 0.775 |
| LVEF (%) | 65(60–68) | 64(60–68) | 64(59–68) | 0.771 |
| ACS subtypes | 0.324 | |||
| UA, n (%) | 474(74.9) | 405(75.4) | 392(72.5) | 0.491 |
| NSTEMI, n (%) | 87(13.7) | 58(10.8) | 74(13.7) | 0.246 |
| STEMI, n (%) | 72(11.4) | 74(13.8) | 75(13.9) | 0.345 |
| Biochemical parameters | ||||
| hs-CRP (mg/L) | 1.21(0.53–3.12) | 1.32(0.66–3.15) | 1.67(0.75–4.67) | <0.001 |
| WBC (109/L) | 5.92(5.12–7.13) | 6.11(5.33–7.25) | 6.92(5.89–7.97) | <0.001 |
| Eosinophils (109/L) | 0.06(0.04–0.07) | 0.11(0.10–0.12) | 0.20(0.17–0.26) | <0.001 |
| Total cholesterol (mmol/L) | 4.21±1.02 | 4.09±0.95 | 4.13±1.00 | 0.103 |
| LDL-C (mmol/L) | 2.35(1.85–3.06) | 2.30(1.84–2.83) | 2.34(1.83–2.97) | 0.097 |
| HDL-C (mmol/L) | 1.05(0.90–1.23) | 0.98(0.85–1.15) | 0.96(0.84–1.10) | <0.001 |
| Triglycerides (mmol/L) | 1.32(0.93–1.82) | 1.51(1.09–2.16) | 1.57(1.04–2.29) | <0.001 |
| Glycosylated hemoglobin A1c (%) | 6.10(5.60–7.20) | 6.00(5.60–6.90) | 6.20(5.60–7.30) | 0.049 |
| FPG (mmol/L) | 5.89(5.27–7.10) | 5.73(5.22–6.68) | 5.78(5.16–7.12) | 0.045 |
| Creatinine (μmol/L) | 70.76±14.28 | 71.55±13.45 | 73.96±17.72 | 0.001 |
Abbreviations: AEC, absolute eosinophil count; ACS: Acute coronary syndrome; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; CAD, coronary artery disease; DM, Diabetes Mellitus; PCI, percutaneous coronary intervention; MI, myocardial infarction; CVA, cerebrovascular accident; PAD, peripheral artery disease; LVEF, left ventricular ejection fraction; UA, unstable angina; NSTEMI, non-ST-segment elevation myocardial infarction; STEMI, ST-segment elevation myocardial infarction; hs-CRP, high-sensitivity C-reactive protein; WBC, white blood cell; LDL-C, low-density lipoprotein-cholesterol; HDL-C, high-density lipoprotein-cholesterol; FPG, fasting plasma glucose.