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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Am J Surg Pathol. 2023 May 1;47(7):756–765. doi: 10.1097/PAS.0000000000002045

Table 2:

Immunophenotypic features and mucin histochemical characterization of mixed ovarian borderline tumors and carcinomas with gastrointestinal-type mucinous and Mullerian epithelial components

Case # Component (predominant cell type) CK7 CK20 ER PR Pax8 CDX2 MUC6 WT1 ARID1A AB/PAS
MO-1 Mucinous (intestinal>gastric) +++ ++ ++ + Loss neutral/acidic
Mullerian (endometrioid) +++ +++ +++ ++ + Loss No intracellular mucin
MO-2 Mucinous (gastric) +++ + + Loss Neutral
Mullerian (endometrioid) +++ + +++ ++ Subclonal loss No intracellular mucin
MO-3 Mucinous (gastric>intestinal) +++ ++ ++ ++ Intact Mixture (neutral>acidic)
Mullerian (endometrioid/clear cell) +++ ++ ++ +++ Intact Only rare cells with mucin (acidic)
MO-4 Mucinous (gastric>intestinal) +++ + + + + ++ Loss Mixture (neutral>acidic)
Mullerian (endometrioid/clear cell) +++ ++ ++ Loss No intracellular mucin

Immunohistochemistry results reported as follows:

, negative;

+

, focal/weak positive;

++

moderate/patchy positive;

+++

, strong/diffuse positive.