Table 1.
Expression of Serum Immunological Molecules in MMD Patients and Healthy Individuals
| Variables | Healthy Individuals (n=70) | MMD Patients | P value | |||
|---|---|---|---|---|---|---|
| Overall (n=84) | Early-Stage (n=46) | Late-Stage (n=38) | P value | |||
| Age, y | 35.5 (29.0–40.5) | 35.0 (24.5–47.0) | 32.0 (22.0–46.0) | 40.0 (29.0–48.0) | 0.075 | 0.502 |
| Sex, male | 34 (48.6%) | 38 (45.2%) | 23 (50.0%) | 15 (39.5%) | 0.335 | 0.680 |
| IgA (g/L) | 12.30 (10.88–13.43) | 1.72 (1.23–2.40) | 1.75 (1.09–2.42) | 1.67 (1.23–2.45) | 0.632 | 0.794 |
| IgG (g/L) | 2.96 (2.42–3.55) | 11.35 (9.25–13.08) | 11.35 (9.09–12.71) | 11.40 (9.79–13.48) | 0.914 | 0.699 |
| IgM (g/L) | 1.06 (0.83–1.49) | 1.03 (0.75–1.39) | 1.07 (0.87–1.39) | 0.93 (0.67–1.39) | 0.371 | 0.618 |
| IgE (IU/L) | 28.14 (14.34–69.35) | 37.72 (10.19–101.55) | 50.96 (12.43–130.75) | 33.29 (6.70–75.84) | 0.310 | 0.578 |
| C3 (mg/dL) | 107.84±14.54 | 99.31±20.08 | 105.57±19.00 | 91.73±18.92 | 0.001** | 0.003** |
| C4 (mg/dL) | 23.40 (20.85–28.10) | 20.94 (16.83–26.28) | 20.75 (17.44–25.41) | 21.29 (16.33–27.56) | 0.677 | 0.943 |
| C3-C4 ratio | 4.46 (3.88–5.16) | 4.72 (3.94–5.61) | 4.79 (4.20–5.82) | 4.37 (3.62–5.02) | 0.026* | 0.261 |
Notes: *P<0.05; **P<0.01.
Abbreviation: IU, indicates international unit.