FIG. 1.
Effect of i.n. infection with CVS-F3 on body weight of mice with different gene defects. Normal 129/SvEv (A, E, and F) and C57BL/6J (B to D) mice (⧫) and the gene k.o. mice (○), rag-2 k.o. (A), β2m k.o. (B), JHD k.o. (C) C3/C4 k.o. (D), IFN-α/βR k.o. (E), and IFN-γR k.o. (F), were infected i.n. with CVS-F3 as described in Materials and Methods. Mice were weighed on a daily basis. Individual body weights were transformed into percentages, taking the weight at day 5 p.i. as 100%. The results are expressed as mean plus standard error of the mean percent body weight of 15 mice per group.