FIG. 3.
Immunohistochemical analysis for rabies virus N protein in coronal sections through the hippocampus of rag-2 k.o. (A to C), β2m k.o. (D to F), JHD k.o. (G to I), IFN-γR k.o. (K to M), C57BL/6J (N to P), and 129/SvEv (R and S) mice infected with CVS-F3. Also shown is a section from a noninfected 129/SvEv mouse (Q). Mice were sacrificed at 8 (A, D, G, K, and N), 13 (B, E, H, L, O, and R), and 21 (C, F, I, M, P, and S) days p.i., and brain sections were prepared and stained with antibodies specific for rabies virus N protein as described in Materials and Methods. Arrows indicate N-protein-positive cells. Areas shown at higher magnification in Fig. 4 are marked by asterisks. Bar = 500 μm.