TABLE 1.

Virus titers in mouse brains following i.n. infection with CVS-F3

Mouse strain	Virus titer (FFU/g of brain)a at indicated days p.i.
	8		13		21
	1	2	1	2	1	2
Rag-2 k.o.	5.0 × 105	1.0 × 105	2.0 × 105	2.5 × 105	1.0 × 106	5.0 × 106
β2m k.o.	7.5 × 103	1.8 × 104	<10	<10	<10	<10
JHD k.o.	2.0 × 104	5.0 × 104	1.5 × 104	5.0 × 104	5.0 × 104	5.0 × 103
C3/C4 k.o.	1.5 × 104	1.0 × 105	<10	<10	<10	<10
IFN-α/βR k.o.	2.5 × 105	2.5 × 105	<10	<10	<10	<10
IFN-γR k.o.	4.0 × 105	5.0 × 104	<10	<10	<10	<10
C57BL/6J	1.0 × 105	1.5 × 105	<10	<10	<10	<10
129/SvEv	7.5 × 103	2.6 × 103	<10	<10	<10	<10

^aDetermined in two mice (1 and 2) for each time point and mouse strain.