TABLE 2.
Titers of VNA from mice infected i.n. with CVS-F3
| Mouse strain | VNA geometric mean titera (range)
|
|
|---|---|---|
| 10 days p.i. | 20 days p.i. | |
| Rag-2 k.o. | 0 | 0 |
| β2m k.o. | 1,265 (810–2430) | 3,028 (1,800–8,100) |
| JHD k.o. | 0 | 0 |
| IFN-α/βR k.o. | 44 (30–90) | 4,446 (1,800–16,200) |
| IFN-γR k.o. | 68 (30–270) | 6,005 (2,700–8,100) |
| C57BL/6J | 581 (135–2,430) | 1466 (600–1,800) |
| 129/SvEv | 455 (270–810) | 16236 (5,460–48,600) |
a
Geometric mean of the reciprocal titer (reciprocal of the highest serum dilution yielding a 50% reduction in test virus, as determined by the fluorescent-focus inhibition assay) of five mice.