Table 2.
Anthropometric and biochemical variables according to the classification criteria
| Non-necrosis | Necrosis | |
|---|---|---|
| Sex (F/M) | 39/17 | 38/16 |
| Age (years) | 45.02 ± 9.01 | 48.57 ± 8.51* |
| Weight (kg) | 132.01 ± 20.15 | 136.43 ± 24.26 |
| BMI (kg/m2) | 47.06 ± 6.41 | 49.67 ± 6.71* |
| Glucose (mg/dl) | 103.44 ± 19.84 | 116.79 ± 33.46* |
| Insulin (µUI/ml) | 15.97 ± 8.72 | 26.21 ± 32.22* |
| HOMA-IR | 4.12 ± 2.27 | 7.48 ± 8.00* |
| Cholesterol (mg/dl) | 184.76 ± 37.27 | 195.53 ± 42.62 |
| Triglycerides (mg/dl) | 126.78 ± 58.34 | 183.02 ± 106.42* |
| HDL-cholesterol (mg/dl) | 44.48 ± 13.44 | 45.08 ± 11.82 |
| LDL-cholesterol (mg/dl) | 115.59 ± 30.41 | 115.44 ± 33.71 |
| GGT (U/l) | 29.93 ± 20.25 | 37.91 ± 30.09 |
| AST (U/l) | 24.67 ± 9.75 | 30.14 ± 13.28 |
| ALT (U/l) | 30.57 ± 14.83 | 35.13 ± 16.42 |
| SBP (mm Hg) | 131.95 ± 22.47 | 132.75 ± 16.58 |
| DBP (mm Hg) | 83.43 ± 12.73 | 84.42 ± 10.75 |
| Histological parameters (n) | ||
| Steatosis grade score (0/1/2/3) | 36/17/0/3 | 0/31/14/9 |
| Necroinflammatory activity grade (0/1/2/3) | 56/0/0/0 | 0/38/16/0 |
| Fibrosis state (0/1/2/3/4) | 56/0/0/0 | 18/19/11/6 |
| Non-steatosis | Steatosis | |
|---|---|---|
| Sex (F/M) | 24/12 | 53/21 |
| Age (years) | 44.31 ± 9.51 | 47.96 ± 8.41* |
| Weight (kg) | 132.95 ± 20.23 | 134.78 ± 23.31 |
| BMI (kg/m2) | 46.95 ± 6.18 | 49.02 ± 6.82 |
| Glucose (mg/dl) | 103.17 ± 22.50 | 113.40 ± 30.04 |
| Insulin (µUI/ml) | 14.35 ± 7.35 | 24.32 ± 28.24* |
| HOMA-IR | 3.72 ± 2.01 | 6.80 ± 7.06* |
| Cholesterol (mg/dl) | 181.57 ± 35.48 | 194.24 ± 41.89 |
| Triglycerides (mg/dl) | 124.14 ± 64.35 | 169.46 ± 96.76* |
| HDL-cholesterol (mg/dl) | 44.03 ± 13.45 | 45.14 ± 12.25 |
| LDL-cholesterol (mg/dl) | 113.74 ± 30.96 | 116.39 ± 32.55 |
| GGT (U/l) | 30.54 ± 21.71 | 35.50 ± 27.56 |
| AST (U/l) | 24.06 ± 9.30 | 29.11 ± 12.77 |
| ALT (U/l) | 29.09 ± 13.04 | 34.65 ± 16.67 |
| SBP (mm Hg) | 134.56 ± 25.18 | 131.25 ± 16.50 |
| DBP (mm Hg) | 84.58 ± 14.53 | 83.58 ± 10.23 |
| Histological parameters (n) | ||
| Steatosis grade score (0/1/2/3) | 36/0/0/0 | 0/48/14/12 |
| Necroinflammatory activity grade (0/1/2/3) | 36/0/0/0 | 20/38/16/0 |
| Fibrosis state (0/1/2/3/4) | 36/0/0/0 | 38/19/11/6 |
| Non-fibrosis | Fibrosis | |
|---|---|---|
| Sex (F/M) | 52/22 | 25/11 |
| Age (years) | 45.99 ± 8.84 | 48.36 ± 8.96 |
| Weight (kg) | 133.43 ± 19.87 | 135.71 ± 26.79 |
| BMI (kg/m2) | 47.87 ± 6.57 | 49.31 ± 6.83 |
| Glucose (mg/dl) | 105.68 ± 22.26 | 118.61 ± 35.89 |
| Insulin (µUI/ml) | 19.69 ± 27.51 | 23.61 ± 13.96* |
| HOMA-IR | 5.08 ± 6.25 | 7.16 ± 5.42* |
| Cholesterol (mg/dl) | 185.08 ± 39.89 | 199.97 ± 39.45 |
| Triglycerides (mg/dl) | 136.70 ± 68.99 | 190.00 ± 113.76* |
| HDL-cholesterol (mg/dl) | 44.59 ± 12.44 | 45.14 ± 13.10 |
| LDL-cholesterol (mg/dl) | 113.66 ± 32.07 | 119.28 ± 31.72 |
| GGT (U/l) | 30.46 ± 20.94 | 40.61 ± 32.67* |
| AST (U/l) | 24.06 ± 9.17 | 32.17 ± 13.75* |
| ALT (U/l) | 30.01 ± 14.00 | 38.39 ± 17.60* |
| SBP (mm Hg) | 131.56 ± 20.55 | 133.92 ± 18.14 |
| DBP (mm Hg) | 84.70 ± 12.39 | 82.31 ± 10.37 |
| Histological parameters (n) | ||
| Steatosis grade score (0/1/2/3) | ||
| Necroinflammatory activity grade (0/1/2/3) | ||
| Fibrosis state (0/1/2/3/4) |
BMI Body mass index, GGT Gamma-glutamyl transferase, AST aspartate aminotransferase, ALT alanine aminotransferase, HOMA-IR homeostasis model assessment of insulin resistance, GGT gamma-glutamyl transferase, SBP systolic blood pressure, DBP diastolic blood pressure
Mann–Whitney test, *p < 0.05 between groups using Mann–Whitney test