Table 3.
Radiological findings in patients with VITT-associated CVST in comparison with patients without VITT
| Finding | VITT-associated CVST (n = 16) | Non-VITT CVST (n = 16) | p value |
|---|---|---|---|
| Cerebral edema on first cerebral imaging, n (%) | 8/16 (50.0) | 12/16 (75) | 0.273 |
| Cerebral congestive / parenchymal hemorrhage on first cerebral imaging, n (%) | 12/16 (75.0) | 12/16 (75) | 1.0 |
| Subarachnoid hemorrhage on first cerebral imaging, n (%) | 3/16 (18.8) | 8/16 (50) | 0.135 |
| Sub-/epidural hemorrhage on first cerebral imaging, n (%) | 3/16 (18.8) | 3/16 (18.8) | 1.0 |
| Any intracranial hemorrhagic lesion on first cerebral imaging, n (%) | 12/16 (75.0) | 14/16 (87.5) | 0.651 |
| Progression of edema on last cerebral imaging before surgery, n (%) | 10/16 (62.5) | 10/16 (62.5) | 1.0 |
| Progression of congestive/parenchymal hemorrhage on last cerebral imaging before surgery, n (%) | 11/16 (68.8) | 6/15 (37.5) | 0.213 |
| Progression of existing or new subarachnoid hemorrhage on last cerebral imaging before surgery, n (%) | 7/14 (50.0) | 0/16 | < 0.001 |
| Progression of existing or new sub-/epidural hemorrhage on last cerebral imaging before surgery, n (%) | 2/14 (14.3) | 1/16 (6.3) | 0.903 |
| Any intracranial hemorrhagic lesion on last cerebral imaging before surgery, n (%) | 13/14 (92.9) | 15/16 (93.8) | 1.0 |
CVST cerebral venous sinus thrombosis, VITT vaccine-induced immune thrombosis with thrombocytopenia