Table 1.
Demographic and clinical characteristics by RLS status
| RLS negative (n = 376) | RLS positive (n = 50) | p value | |
|---|---|---|---|
| Age (n = 426) | 49.5 (11.1) | 53.5 (12.3) | 0.02 |
| Female gender (n = 426) | 234 (62.2%) | 38 (76.0%) | 0.06 |
| White (n = 426) | 281 (74.7%) | 40 (80%) | 0.42 |
| PSQI > 5 (n = 423) | 136 (36.5%) | 31 (62.0%) | 0.0005 |
| ESS > 10 (n = 424) | 35 (9.4%) | 7 (14.0%) | 0.31 |
| High risk for OSA (n = 424) | 37 (9.9%) | 6 (12.0%) | 0.64 |
| IRLS severity score (n = 50) | – | 10.2 (4.4) | – |
| Hypertension (n = 426) | 64 (17.0%) | 7 (14.0%) | 0.59 |
| Diabetes (n = 426) | 17 (4.5%) | 5 (10.0%) | 0.16 |
| Hyperlipidemia (n = 426) | 86 (22.9%) | 13 (26.0%) | 0.62 |
| Current or past smoking (n = 424) | 65 (17.4%) | 14 (28.0%) | 0.07 |
| Current alcohol use (n = 423) | 310 (83.1%) | 40 (80.0%) | 0.58 |
| BMI (n = 389) | 27.1 (6.1) | 26.7 (6.3) | 0.72 |
| Serum ferritin (n = 374) | 86.3 (83.2) | 75.0 (69.2) | 0.39 |
| Hemoglobin (n = 372) | 14.0 (2.1) | 13.4 (1.4) | 0.02 |
| Hematocrit (n = 372) | 41.3 (4.7) | 39.8 (3.9) | 0.049 |
| Creatinine (n = 374) | 1.1 (4.5) | 0.8 (0.2) | 0.33 |
| LDL, mg/dL (n = 373) | 108.1 (30.0) | 106.8 (31.0) | 0.79 |
| HDL, mg/dL (n = 372) | 61.3 (18.0) | 64.0 (20.9) | 0.34 |
Bold entries indicate statistical significance
Data are presented as mean (standard deviation) or number (percent)
BMI body mass index, BUN blood urea nitrogen, Cr creatinine, ESS Epworth Sleepiness Scale, HDL high density lipoprotein, IRLS International RLS study group severity scale, LDL low density lipoprotein, OSA obstructive sleep apnea, PSQI Pittsburgh Sleep Quality Index, RLS restless legs syndrome