Table 5.

Subclinical cardiovascular disease measures and association with PLMS

	F value for relationship with PLMI	Univariate p value*	Covariate adjusted p value**
Reactive hyperemia index (n = 39)	5.24	0.03	0.70
Flow mediated dilation %, controlling for baseline diameter (n = 39)	1.08	0.30
Augmentation index, controlling for height and heart rate (n = 39)	4.20	0.049	0.89
Pulse wave velocity, m/s (n = 38)	1.23	0.27	–
Mean carotid IMT, mm (n = 39)	8.0	0.008	0.04

Bold entries indicate statistical significance

Table represents linear regression of PLMI predicting each subclinical cardiovascular disease measure

IMT intima-media thickness, PLMI periodic limb movement index

*Univariate p value reflects the relationship between PLMI and the variable of interest, in univariate linear regression for reactive hyperemia index, pulse wave velocity, and mean carotid IMT and multiple linear regression for augmentation index (including height, also controlled for heart rate) and flow mediated dilation (including baseline diameter)

**Covariate adjusted analyses were performed in the case of significant univariate associations, and were additionally controlled for age, hypertension, hyperlipidemia, log pAHI, and RLS status; p values reflect the p value for the relationship between PLMI and the variable of interest in the multivariate model