Table 3.

Treatment Protocols

Author	PRP Characteristics	PRP Protocol	Rehabilitation
Alessio-Mazzola et al.9	Mean platelet concentration: 600,000 Leukocyte-poor leukocytes: <1000 WBC/mL23	Number of injections: 4 Interval: 1 wk Volume: 5 mL	NSAIDs discouraged, no formal exercise or PT, allowed gradual return to work and sports
Blanke et al.16	Leukocyte poor Type 3A class (Mishra et al.24)	Number of injections: 3 Interval: 1 wk Volume: 2-5 mL	Allowed to weight bear, avoid physical activity for 4 wk, NSAIDs not allowed for 6 mo, no formal PT
Guenoun et al.10	Platelet concentration: 497 ± 154 G/L 0.1% leukocytes: 0.58 ± 0.51 G/L	Number of injections: 1 Volume: 4 mL	NR
Kaminski et al.19	Red-L-PRPIIB-1 class Contains leukocytes	Number of injections: 1 Volume: 6-8 mL Concomitant ultrasound-guided meniscal trephination	Referred to PT, hinged knee brace for 4 wk, ROM for 6 wk, weightbearing as tolerated, slow increase in exercises from 6 to 12 wk onward
Medina-Porqueres et al.17	NR	Number of injections: 3 Interval: 1 wk Volume: 6 mL	Avoid NSAIDs for 2 wk after last injection, apply ice and full weightbearing, avoid impact activities for 2 wk with gradual return over 4 to 8 wk
Ozyalvac et al.18	Type 2B class (Mishra et al.24)	Number of injections: 1 Volume: 4 mL	NR

NR, not recorded; NSAID, nonsteroidal anti-inflammatory drug; PRP, platelet-rich plasma; PT, physical therapy; ROM, range of motion; WBC, white blood cells.