Table 3.
Nomograms on pre-treatment prediction of biochemical recurrence in men treated with radiotherapy
Study | Prediction model | BCR (years) | Radiation type | No of patients | Variables | Discrimination |
---|---|---|---|---|---|---|
Zagars et al71 | Probability graph | 6 | EBRT | 938 | PSA, biopsy GS, CS | NA |
D'Amico et al72 | Probability table | 2 | EBRT | 762 | Biopsy GS, CS, PSA | NA |
Shipley et al73 | Probability table | 5 | EBRT | 1607 | Biopsy GS, CS, PSA | NA |
Kattan et al74 | Probability nomogram development | 5 | EBRT | 1042/1030 | PSA, biopsy GS, CS, neoadjuvant ADT, radiation dose delivered | 73% |
D'Amico et al75 | Probability graph | 5 | EBRT | 766 | Biopsy GS, CS, PSA, treatment modality | NA |
Ragde et al76 | Risk group | 10 | BT | 98 | Age, biopsy GS, CS, PSA, 45 Gy EBRT | 76% |
Kattan et al12 | Probability nomogram development | 5 | BT | 920, 1827, 765 | Biopsy GS, CS, PSA, co-administration of EBRT | 61–64% |
BCR, biochemical recurrence; EBRT, external beam radiotherapy; BT, brachytherapy; GS, Gleason sum; ADT, androgen deprivation therapy; NA, not available.