FIGURE 5.

(A) ICV‐BDNF treatment induced Beclin‐1 protein levels and positive cells in the penumbra area after CI. The groups marked with different symbols were statistically different from each other (p < 0.05). There is the same β‐actin gel image below the gel images of Beclin‐1, LC3, p62, caspase‐3 genes. (Beclin‐1 (green) with the nuclei counterstained by DAPI (blue). Scale bar = 50 μm). (B) ICV BDNF treatment induced LC3‐II/I protein and LC3 positive cells after CI. The groups marked with different symbols were statistically different from each other (p < 0.05). There is the same β‐actin gel image below the gel images of Beclin‐1, LC3, p62, caspase‐3 genes. (LC3 (green) with the nuclei counterstained by DAPI (blue). Scale bar = 50 μm). (C) ICV BDNF treatment reduced p62 protein levels and positive cells after CI. The groups marked with different symbols were statistically different from each other (p < 0.05). There is the same β‐actin gel image below the gel images of Beclin‐1, LC3, p62, caspase‐3 genes. (p62 (green) with the nuclei counterstained by DAPI (blue). Scale bar = 50 μm).