Table 3.

The mean values of Shapley Additive exPlanations on the internal and external validation sets.

Variables	Internal validation, mean (SD)	External validation, mean (SD)
eGFRa CKD-EPIb	0.076 (0.09)	0.063 (0.088)
Average dose of vancomycin	0.045 (0.05)	0.04 (0.073)
Average volume of distribution	0.037 (0.029)	0.032 (0.04)
Interval of vancomycin	0.028 (0.014)	0.031 (0.03)
Body weight	0.027 (0.038)	0.024 (0.044)
Total dose	0.014 (0.028)	0.02 (0.066)
Height	0.013 (0.023)	0.015 (0.026)
Sex	0.01 (0.018)	0.011 (0.004)
Number of vancomycin injection	0.01 (0.012)	0.015 (0.031)
Creatinine	0.01 (0.007)	0.01 (0.011)
Loading	0.007 (0.012)	0.003 (0.01)
Age	0.006 (0.006)	0.006 (0.003)
Dialysis	0.005 (0.018)	0.005 (0.028)
The elimination rate constant at infusion time	0.005 (0.022)	0.005 (0.022)
Time between vancomycin injection and TDMc	0.003 (0.002)	0.007 (0.007)

^aeGFR: estimated glomerular filtration rate.

^bCKD-EPI: Chronic Kidney Disease Epidemiology Collaboration.

^cTDM: therapeutic drug monitoring.