Table 2.

High-dose DT (50 ng/g): Density of type I or type II HCs.

UTRICLE (Data for Figure 1G)
Genotype	Time	Type I HCs*	SIG. DIFFS. PER ONE-WAY ANOVA: HCI***	Type II HCs*	SIG. DIFFS. PER ONE-WAY ANOVA: HCII***	N	HCI: % of control**	HCII: % of control**
Wildtype (WT)**	70d pDT	93 ± 17	p ≤ 0.0001 for DTR 14, 42, 70, 140, 395d	92 ± 21	p ≤ 0.01 for DTR 140d; p ≤ 0.001 for DTR 70; p ≤ 0.0001 for DTR 14, 42, 395d	3	–	–
DTR	14d pDT	11 ± 9	p ≤ 0.0001 for WT	10 ± 5	p ≤ 0.0001 for WT; p ≤ 0.05 for DTR 70d; p ≤ 0.01 DTR for 140d	3	12	11
	42d pDT	12 ± 5	p ≤ 0.0001 for WT	28 ± 10	p ≤ 0.0001 for WT	3	13	30
	70d pDT	6 ± 4	p ≤ 0.0001 for WT	41 ± 2	p ≤ 0.001 for WT; p ≤ 0.05 DTR 14d	3	6	45
	140d pDT	3 ± 2	p ≤ 0.0001 for WT	47 ± 5	p ≤ 0.01 for WT and for DTR 14d	3	3	51
	395d pDT	2 ± 1	p ≤ 0.0001 for WT	30 ± 1	p ≤ 0.0001 WT	3	2	33
AMPULLA (Data for Figure 2G)
Genotype	Time	Type I HCs*	SIG. DIFFS. PER ONE-WAY ANOVA: HCI***	Type II HCs*	SIG. DIFFS. PER ONE-WAY ANOVA: HCII***	N	HCI: % of control**	HCII: % of control**
Wildtype (WT)**	14d (n = 1) & 42d pDT (n = 2)*	82 ± 9	p ≤ 0.0001 for DTR 14, 42d; p ≤ 0.001 for 170d	86 + 11	p ≤ 0.001 for DTR 170; p ≤ 0.0001 for DTR 14, 42d	3	–	–
DTR	14d pDT	15 ± 5	p ≤ 0.0001 for WT	6 ± 2	p ≤ 0.0001 for WT; p ≤ 0.01 for 42, 170d	3	19	8
	42d pDT	12 ± 4	p ≤ 0.0001 for WT	6 ± 3	p ≤ 0.0001 for WT	3	15	7
	170d pDT	19 ± 7	p ≤ 0.001 for WT	17 ± 4	p ≤ 0.001 for WT	2	9	41

*HCs per 10,000 μm² (Avg ± SD).

***Shows groups significantly different from the group in gray shading on left.

**WT controls received 25 ng/g DT.