Table 3.

Low-dose DT (25 ng/g): Counts for all HCs (type I plus type II).

UTRICLE (Data for Figure 10K)
Genotype	Time	HCs per organ (Avg ± SD)	% of control*	N	SIG. DIFFS.PER ANOVA
Wildtype	No DT	3,779 ± 114	–	4	p ≤ 0.0001 for DTR 14, 42, 70, 140, 170, 445d
	14d pDT	3,824 ± 13	–	3	" " " " " " "
DTR	No DT	3,646 ± 275	–	4	" " " " " " "
	14d pDT	826 ± 317	22%	5	p ≤ 0.0001 all controls and p ≤ 0.01 DTR 140d
	42d pDT	807 ± 78	21%	5	p ≤ 0.0001 all controls and p ≤ 0.05 DTR 140d
	70d pDT	1,051 ± 225	27%	3	p ≤ 0.0001 all controls
	140d pDT	1,339 ± 242	35%	4	p ≤ 0.0001 all controls; p ≤ 0.01 DTR 14d; p ≤ 0.05 DTR 42d
	170d pDT	971 ± 148	25%	3	p ≤ 0.0001 all controls
	445d pDT	1,180 ± 215	31%	3	p ≤ 0.0001 all controls

AMPULLA (Data for Figure 10L)
Genotype	Time	HCs per organ (Avg ± SD)	% of control*	N	SIG. DIFFS. PER ANOVA
Wildtype	No DT	855 ± 37	–	2	p ≤ 0.0001 for DTR 14, 42, 70, 140, 170, 445d
	14d pDT	916 ± 21	–	4	" " " " " " "
DTR	No DT	887 ± 70	–	3	" " " " " " "
	14d pDT	164 ± 80	18%	5	p ≤ 0.0001 all controls
	42d pDT	115 ± 14	13%	5	p ≤ 0.0001 all controls and p ≤ 0.05 DTR 140d
	70d pDT	119 ± 11	13%	3	p ≤ 0.0001 all controls
	140d pDT	244 ± 81	27%	4	p ≤ 0.0001 all controls; p ≤ 0.05 DTR 42d
	170d pDT	115 ± 26	13%	3	p ≤ 0.0001 all controls

*WT, 14d pDT.