Table 3.

Results of Paired Pre–Direct-Acting Antiviral Agent (DAA) Therapy and Post–DAA Therapy Biopsies

Sex	Age, y	Pre-Tx Grade	Pre-Tx Stage	Pre-Tx PIR	DAA-SVR Grade	DAA-SVR Stage	DAA-SVR PIR	Duration of Tx, wk	Time Interval Between Biopsies, y
Male	41	1	1		2	2		12	18
Male	60	2	2		1	2		12	2
Female	56	3	2		1	4		12	6
Male	62	2	4	I	1	4	P	12	2
Female	53	2	2		0	2		12	1
Male	66	3	3		0	2		12	5
Male	61	4	3		2	2		N/A	17
Male	64	3	4	P	3	4	P	24	2
Male	64	2	2		2	4	I	12	2
Male	61	2	4	P	2	4	I	24	16
Male	64	2	4	P	1	4	R	24	1
Male	63	3	4	P	2	4	P	24	11
Male	50	3	4	P	1	4	P	26	10
Male	66	2	4	P	1	3–4	R	45	2

Abbreviations: N/A, not available; PIR, progressive, indeterminate, and regressive fibrosis; SVR, sustained viral response; Tx, therapy.