Table 3.

Comparison of child-reported and parent-reported fatigue scores between patients and comparisons over time

	Group Main Effect			Group by Time interaction		Time 1			Time 2			Time 3
Child report	Mean differencea (95% CI)	Effect size	p	Χ2 (df)	p	Mean differencea (95% CI)	Effect size	p	Mean differencea (95% CI)	Effect size	p	Mean differencea (95% CI)	Effect size	p
Total fatigue	4.92 (-0.02, 9.86)	0.28	0.051	2.04 (2)	0.360	3.89 (-2.11, 9.90)	0.23	0.203	3.13 (-3.20, 9.46)	0.18	0.332	7.70 (1.30, 14.11)	0.45	0.018
General fatigue	5.34 (0.014, 10.53)	0.28	0.044	0.53 (2)	0.976	5.65 (-0.95, 12.25)	0.30	0.093	5.00 (-1.98, 11.99)	0.26	0.160	4.82 (-2.27, 11.90)	0.25	0.183
Sleep/rest fatigue	4.04 (-1.31, 9.39)	0.20	0.139	2.60 (2)	0.272	2.03 (-5.00, 9.07)	0.10	0.571	1.97 (-5.50, 9.44)	0.10	0.605	8.32 (0.74, 15.90)	0.41	0.031
Cognitive fatigue	5.78 (-0.81, 12.37)	0.24	0.086	2.33 (2)	0.311	4.26 (-4.02, 12.53)	0.18	0.313	3.10 (-5.66, 11.86)	0.13	0.488	10.21 (1.34, 19.08)	0.43	0.024
Parent report	Mean differencea (95% CI)	Effect size	p	Χ2 (df)	p	Mean differencea (95% CI)	Effect size	p	Mean differencea (95% CI)	Effect size	p	Mean differencea (95% CI)	Effect size	p
Total fatigue	12.10 (7.37, 16.82)	0.76	< 0.001	4.13 (2)	0.127	13.87 (8.63, 19.11)	0.87	< 0.001	9.47 (4.02, 14.91)	0.60	0.001	13.07 (7.57, 18.57)	0.82	< 0.001
General fatigue	13.41 (8.47, 18.34)	0.76	< 0.001	8.55 (2)	0.014	17.02 (11.26, 22.77)	0.97	< 0.001	8.56 (2.52, 14.60)	0.49	0.005	14.35 (8.23, 20.47)	0.82	< 0.001
Sleep/rest fatigue	9.49 (4.65, 14.33)	0.58	< 0.001	4.27 (2)	0.118	12.43 (6.85, 18.00)	0.76	< 0.001	6.80 (0.97, 12.64)	0.42	0.022	8.74 (2.83, 14.64)	0.53	0.004
Cognitive fatigue	13.22 (7.08, 19.36)	0.65	< 0.001	1.58 (2)	0.454	12.19 (5.37, 19.01)	0.60	< 0.001	12.87 (5.78, 20.00)	0.63	< 0.001	15.78 (8.62, 22.94)	0.78	< 0.001

^a Comparison group–patient group. Time 1 = 3-months post-treatment completion. Time 2 = 15-months post-treatment completion. Time 3 = 27-months post-treatment completion