Table 2.
Effects of HTX against Plasmodium parasites in malaria-infected mice
| Groups | Dose (mg/kg) | % parasitemia | % suppression |
|---|---|---|---|
| Negative control | - | 33.49 ± 3.01 | - |
| Artesunate | 3 | 3.84 ± 0.54 | 91.26 ± 3.54 c, d, e |
| Chloroquine | 3 | 3.42 ± 0.35 | 92.07 ± 4.21 c, d, e |
| HTX | 1 | 21.91 ± 2.25 | 34.56 ± 4.91 a, b, d, e |
| HTX | 3 | 17.79 ± 2.31 | 46.88 ± 3.96 a, b, c, e |
| HTX | 10 | 8.62 ± 1.21 | 74.26 ± 3.32 a, b, c, d |
Data represent the mean ± SEM (n = 5 per group). Values are significantly different at p < 0.05 : different superscript letters. acompared with artesunate; bcompared with chloroquine; ccompared with 1 mg/kg HTX; dcompared with 3 mg/kg HTX; ecompared with 10 mg/kg HTX.