7. Specific adverse events to medication.

Adverse events	Study	One or two daily doses (n/N)	Three daily doses (n/N)	Risk ratio	95% CI
Diarrhoea	Principi 1986	1/55	1/55	1.00	0.06 to 16.40
	Hoberman 1997	16/287	20/288	0.80	0.42 to 1.52
	Behre 1997	15/231	24/232	0.63	0.34 to 1.17
	Damrikarnlert 2000	15/209	22/206	0.65	0.3 to 1.28
Skin adverse events	Principi 1986	3/55	3/55	1.00	0.19 to 5.19
	Hoberman 1997	23/287	30/288	0.77	0.46 to 1.29
	Damrikarnlert 2000	2/209	5/206	0.39	0.07 to 2.02

CI: confidence interval