Table 5.
Key challenges for the stem cell harvest and engraftment.
| Challenges | Intervention | Result | Future |
|---|---|---|---|
| Assumed difficulty in the pre- harvest enumeration | Inj. PLERIXAFOR 24 mg S/C for all patients during 1st camp | Adequate stem cell collection (except one patient who required 2 days collection) | Camp 2- Reliable CD34 cell enumeration – Inj. PLERIXAFOR required only for 1 patient |
| Limitation in the number of apheresis kits and consumables | |||
|
| |||
| Venous access | CVC (femoral)- camp 1–5 patients | Apheresis procedure uneventful | Camp 2- CVC required only for 1 patient |
|
| |||
| Febrile neutropenia management | Inj. Peg G-CSF 6 mg SC weekly from day +3 until engraftment | Early engraftment | |