Table 2.
Multivariate analysis with the Cox proportional hazards model of overall survival in patients with primary EwS of the sacrum (main analysis was OS).
| P | Hazard ratio | 95% confidence interval | ||
|---|---|---|---|---|
| Lower | Upper | |||
| Sex (male/female) | 0.26 | 1.58 | 0.71 | 3.52 |
| Metastases at diagnosis | <0.001 | 4.23 | 1.84 | 9.70 |
| Tumor volume (≥200 mL/<200 mL) | 0.04 | 2.14 | 1.03 | 4.46 |
| Study protocol (GPOH EE99/EWING2008) | 0.25 | 1.64 | 0.70 | |
| Age group (≥18 years/<18 years) | 0.01 | 2.92 | 1.29 | 6.60 |
| Surgery | 0.06 | |||
| Surgery ∗ radiotherapy | 0.02 | 0.17 | 0.04 | 0.74 |
| Radiotherapy | 0.10 | 0.33 | 0.09 | 1.21 |