Table 3.
HRs and 95% CI for immune cell proportions and liver cancer, in the Strong Heart Study
| Immune cell subtype | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | |
| CD8+ | 1.44 (0.99, 2.10) | 0.06 | 1.46 (1.02, 2.10) | 0.04 | 1.14 (0.70, 1.85) | 0.61 |
| CD4+ | 0.92 (0.59, 1.44) | 0.72 | 0.96 (0.62, 1.51) | 0.87 | 0.82 (0.50, 1.36) | 0.45 |
| Natural killer | 1.55 (1.07, 2.26) | 0.02 | 1.54 (1.05, 2.26) | 0.03 | 1.41 (0.85, 2.33) | 0.18 |
| B-lymphocytes | 1.36 (0.93, 2.00) | 0.12 | 1.35 (0.93, 1.96) | 0.12 | 1.37 (0.89, 2.12) | 0.16 |
| Monocytes | 1.09 (0.71, 1.65) | 0.7 | 1.03 (0.69, 1.56) | 0.87 | 0.88 (0.55, 1.42) | 0.61 |
| Granulocytes | 0.69 (0.44, 1.07) | 0.09 | 0.67 (0.43, 1.04) | 0.08 | 0.69 (0.41, 1.01) | 0.1 |
The HR is reported per SD of proportion for each cell counts
Model 1: age, sex and center
Model 2: model 1 + alcohol (ever/current vs never), smoking (ever/current vs never), BMI and LDL