Table 2.

Spearman Rho’s correlations among outcomes and covariates

	Pain status	Sex	Race	Income	BMI	Horvath EAA	Hannum EAA	PhenoAge EAA	Chrono Age	Dunedin PACE	Pain Severity
Pain status	1
Sex	−0.017	1
Race	0.162	0.017	1
Income	.234*	0.003	.229*	1
BMI	−.237*	0.081	−.332**	−0.158	1
Horvath EAA	0.181	0.007	0.074	−0.005	−0.048	1
Hannum EAA	0.034	0.028	.210*	0.048	−0.087	.674**	1
PhenoAge EAA	−0.035	0.1	0.153	−0.051	0.071	.420**	.417**	1
Chrono Age	−.221*	−0.056	−0.084	0.049	0.106	−.565**	−.594**	−.207*	1
Dunedin PACE	−.359**	0.083	−.364**	−.328**	.513**	−.264**	−.240**	0.119	.409**	1
Pain Severity	−.849**	0.049	−.247**	−.377**	.257**	−.232*	−0.088	−0.053	.298**	.453**	1
Pain Interference	−.819**	0.065	−.193*	−.342**	.302**	−.265**	−0.13	−0.002	.287**	.476**	.885**

^*Correlation is significant at the 0.05 level

^**Correlation is significant at the 0.01 level

BMI = body mass index; EAA = Epigenetic age acceleration measured as the difference between epigenetic age and chronological age.