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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: J Invest Dermatol. 2023 Nov 17;144(4):888–897.e6. doi: 10.1016/j.jid.2023.10.015

Figure 2. Reproducible cutaneous wounds can be made with a rotary tool.

Figure 2.

(a-b) Images of a male and female fish before and after cutaneous wounding with a 1/16th inch drill bit (small wound) (a) or 1/8th inch drill bit (large wound) (b), showing consistent wound formation using a rotary tool. (c) Quantification of wound area for small (n=13) and large wounds (n=8), with each dot representing a single fish. (d-e) Confocal images of fixed and DAPI stained shallow (d) and deep (e) cutaneous wounds showing XY, XZ, and YZ planes. (f) Quantification of wound depth for shallow (n=4) and deep wounds (n=6), with each dot representing a single fish. Error bars in C and F indicate mean +/− SD. Images are oriented anterior left and dorsal up. Scale bars = 5000μm (a-b), and 1000μm (d-e).