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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: J Invest Dermatol. 2023 Nov 17;144(4):888–897.e6. doi: 10.1016/j.jid.2023.10.015

Figure 5. Macrophage recruitment and activation in cutaneous wounds.

Figure 5.

(a) Confocal images of adult Tg(mpeg:eGFP)gl22 transgenic fish labeling macrophages (green) before and after cutaneous injury and at intervals thereafter up to 15dpi. (b) Representative images of macrophages with varying degrees of ellipticity with the higher number showing a rounder shape indicating a more activated phenotype. (c) Graph showing the total number of macrophages, and the number of macrophages with ellipticity values between 0–0.4, 0.4–0.6, and 0.6–1 within the wound site over 30dpi (n=6 fish). Dotted green line depicts average number of macrophages in uninjured controls. (d) Graph depicting the percent of macrophages with indicated ellipticity phenotype out of total number of macrophages at indicated timepoint from 1–30dpi including uninjured control (n=6 fish). Chi-square test, *p<0.05, **p<0.01. Images are oriented anterior left and dorsal up. Scale bars = 1000μm (a).