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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: J Invest Dermatol. 2023 Nov 17;144(4):888–897.e6. doi: 10.1016/j.jid.2023.10.015

Figure 6. Revascularization of cutaneous wounds.

Figure 6.

Confocal images of uninjured (a-c) and injured (e-v) Tg(mrc1a:eGFP)y251, Tg(kdrl:mcherry)y206 double transgenic, casper mutant adult fish with ossified structures blue (autofluorescence), lymphatic vessels green (mrc1a:eGFP), and blood vessels magenta (kdrl:mCherry). Whole-fish overview (a) and magnified flank images of lymphatic (b) or blood vessels (c). White dotted box in A depicts injury area for E-V. (d) Quantification of percent (%) vessel regrowth for lymphatic (green) and blood (magenta) vessels at time points following cutaneous injury (n=4 fish). Error bars indicate mean +/− SEM. (e-v) Images showing one fish before cutaneous injury (e,k,q), after injury (f,l,r), and at several time points thereafter through 10 dpi (g-v). Merged images (e-j) or lymphatic (k-p) and blood (q-v) vessel only are shown. Images are oriented anterior left and dorsal up. Scale bars = 5000μm (a), and 1000μm (b-c, e-v).