Table 2.

Biochemical findings

Characteristics	Baseline (earliest available data)	At time of pseudocirrhosis diagnosisa	Last valueb
Laboratory data, median (IQR)
Alkaline phosphatase (U/L)	70 (44–124)	182 (135–286)*	263 (148.5–509)*
Total protein (g/dL)	7.2 (6.6–7.5)	6.7 (6.0–7.5)	6.7 (5.3–7.2)*
Albumin (g/dL)	4.2 (3.8–4.5)	3.5 (3.0–3.9)*	3.3 (2.8–3.6)*
Total bilirubin (mg/dL)	0.4 (0.2–0.7)	0.5 (0.4–0.9)*	1 (0.5–3.0)
ALT (U/L)	19 (15–28)	25 (19–45)	39 (19–102.5)*
AST (U/L)	22 (19–29)	54 (36–98)*	68.5 (46–116)*
INR	1.0 (0.9–1.0)	1.1 (1.0–1.2)*	1.3 (1.1–1.7)*
R factor	0.82 (0.4–1.88)	0.42 (0.27–0.57)*	0.39 (0.22–0.87)*
Platelet count	214 (188–252.5)	179 (122–265)	175 (89–266)

*p < 0.05 after Tukey’s adjustment for the comparison with the baseline value

^aDays from baseline to pseudocirrhosis diagnosis, Median (IQR): 70 (14–259)

^bDays from pseudocirrhosis diagnosis to last value, Median (IQR): 1108.5 (815–2012)