Table 3.
Factors associated with reduced work status (versus maintained work status) from diagnosis to survey among 845 Norwegian breast cancer survivors who were in paid work at diagnosis and within working age at survey
| Univariable analyses* | Multivariable analysis | ||||
|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | p | |
| Socio-demographic variables | |||||
| Living with partner | |||||
| Yes (reference) | 1.0 | 1.0 | |||
| No | 1.22 | 0.88–1.68 | 1.09 | 0.69–1.72 | 0.71 |
| Living with children < 18 years | |||||
| Yes (reference) | 1.0 | 1.0 | |||
| No | 1.56 | 1.09–2.24 | 0.44 | 0.24–0.82 | 0.01 |
| Years of education | |||||
| > 12 years (reference) | 1.0 | 1.0 | |||
| ≤ 12 years | 1.18 | 0.89–1.57 | 0.91 | 0.61–1.37 | 0.66 |
| Cancer-related variables | |||||
| Age at diagnosis | 1.07 | 1.04–1.09 | 1.16 | 1.11–1.21 | < .001 |
| Systemic treatment burden | |||||
| No systemic treatment (reference) | 1.0 | 1.0 | |||
| Chemotherapy alone | 1.66 | 0.95–2.91 | 2.83 | 1.24–6.61 | 0.01 |
| Endocrine therapy alone | 2.11 | 1.11–4.0 | 1.32 | 0.56–3.08 | 0.52 |
| Chemotherapy and endocrine therapy | 1.20 | 0.76–1.89 | 1.12 | 0.59–2.13 | 0.73 |
| Chemotherapy and trastuzumab | 0.79 | 0.36–1.72 | 0.66 | 0.19–2.24 | 0.50 |
| Chemotherapy, trastuzumab, endocrine therapy | 1.49 | 0.87–2.55 | 1.51 | 0.70–3.28 | 0.30 |
| Health variables | |||||
| Somatic comorbid conditions | |||||
| 0 (reference) | 1.0 | 1.0 | |||
| 1–2 | 2.26 | 1.57–3.26 | 1.42 | 0.86–2.34 | 0.17 |
| > 2 | 4.75 | 3.01–7.50 | 2.27 | 1.16–4.32 | 0.02 |
| Sleep problems | |||||
| No (reference) | 1.0 | 1.0 | |||
| Yes | 1.90 | 1.43–2.53 | 1.41 | 0.93–2.14 | 0.10 |
| Neuropathy | |||||
| Low (reference) | 1.0 | 1.0 | |||
| High | 2.56 | 1.82–3.61 | 1.41 | 0.86–2.32 | 0.17 |
| Cognitive function | 0.98 | 0.97–0.99 | 0.99 | 0.98–.99 | 0.04 |
| Pain | 1.02 | 1.02–1.03 | 1.0 | 0.99–1.01 | 0.99 |
| Fatigue | 1.03 | 1.02–1.03 | 1.02 | 1.01–1.03 | < .001 |
| Arm symptoms | 1.01 | 1.01–1.02 | 1.01 | 0.99–1.02 | 0.23 |
| Breast symptoms | 1.02 | 1.01–1.02 | 0.99 | 0.99–1.01 | 0.68 |
| Depressive symptoms | 1.09 | 1.06–1.13 | 0.95 | 0.88–1.0 | 0.09 |
| Fear of cancer recurrence | 1.03 | 1.01–1.04 | 1.0 | 1.0–1.03 | 0.73 |
| Neuroticism | |||||
| No (reference) | 1.0 | 1.0 | |||
| Yes | 1.29 | 1.19–1.39 | 1.57 | 1.0–2.46 | 0.04 |
| Health literacy | 0.97 | 0.94–0.99 | 0.99 | 0.96–1.03 | 0.82 |
Bold indicates statistically significant
*Only variables associated with reduced work status in univariable analyses with p < 0.25 are displayed in the table