Table 1.
Organ weights.
| WT saline | Nox2 KO saline | WT Dox | Nox2 KO Dox | |
|---|---|---|---|---|
| BW (g) | 24.4 ± 1.1 | 25.4 ± 1.1 | 23.5 ± 1.2 | 22.9 ± 1.0 |
| TL (mm) | 17.7 ± 0.2 | 17.8 ± 0.2 | 17.7 ± 0.1 | 17.9 ± 0.1 |
| THW (mg) | 119.2 ± 4.1 | 121.3 ± 4.7 | 98.9 ± 3.7 | 105.0 ± 7.6 |
| THW/TL (mg/mm) | 6.08 ± 0.27 | 6.29 ± 0.20 | 4.71 ± 0.16* | 5.80 ± 0.34# |
| Liver W (wet/dry) | 3.06 ± 0.10 | 3.21 ± 0.09 | 3.15 ± 0.11 | 3.20 ± 0.07 |
| Lung W (wet/dry) | 4.35 ± 0.11 | 4.17 ± 0.09 | 4.96 ± 0.22* | 4.08 ± 0.09# |
Values are mean ± S.E.M. N = 9–14.
WT wild type, KO knockout, Dox doxorubicin, BW body weight, TL tibial length, THW total heart weight, W weight.
*P < 0.05 versus WT saline group. #P < 0.05 versus WT Dox group.