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. 2024 Mar 23;25:139. doi: 10.1186/s12931-024-02764-8

Table 2.

Description of urinary DEHP metabolites comparisons between cases and controls, and among 6 phenotypic clusters and controls

Urinary metabolites (µg/g creatinine) Control Case Cluster A Cluster B
Median (IQR) Median (IQR) Median (IQR) Median (IQR)
MEHP 5.48 (6.77) 8.74 (13.22)*** 10.69 (10.40) 7.95 (8.92)
MEHHP 11.86 (11.34) 20.63 (21.38)*** 25.93 (16.60)** 16.71 (13.44)
MEHP + MEHHP 18.20 (15.46) 30.73 (34.17)*** 39.16 (35.26)** 26.35 (24.63)
MEHHP/MEHP 2.14 (2.20) 2.49 (2.55) 2.54 (3.82) 2.46 (2.02)
Urinary metabolites (µg/g creatinine) Cluster C Cluster D Cluster E Cluster F
Median (IQR) Median (IQR) Median (IQR) Median (IQR)
MEHP 11.42 (19.01)** 104.75 (482.75)* 10.71 (19.80) 5.84 (10.79)
MEHHP 20.70 (21.37)*** 196.72 (893.00)*** 20.34 (36.20) 19.65 (16.99)***
MEHP + MEHHP 30.74 (58.29)*** 301.47 (1375.64)*** 36.88 (40.15) 25.01 (26.89)**
MEHHP/MEHP 2.44 (2.01) 3.50 (2.78) 1.93 (7.89) 2.62 (2.26)
Urinary metabolites (µg/g creatinine) P-valuea P-valueb
MEHP < 0.001 < 0.001
MEHHP < 0.001 < 0.001
MEHP + MEHHP < 0.001 < 0.001
MEHHP/MEHP 0.097 0.563

a Tested by Mann–Whitney U test

b Tested by Kruskal–Wallis H test and Bonferroni correction

* P < 0.05; ** P < 0.01; *** P < 0.001