. 2024 Mar 23;25:139. doi: 10.1186/s12931-024-02764-8

Table 3.

Current asthma and its phenotypic clusters in relation to DEHP exposures

Urinary metabolites		Case vs. control (n = 80/33)		Cluster A/control (n = 14/143)		Cluster B/control (n = 23/143)		Cluster C/control (n = 13/143)
Urinary metabolites		ORs	P-value^a	OR	P-value^b	OR	P-value^b	OR	P-value^b
Model 1	MEHP	1.39	0.07	1.57	0.01	1.26	0.11	1.78	< 0.001*
Model 2	MEHHP	4.49	< 0.001*	2.86	< 0.001*	1.90	0.003	2.94	< 0.001*
	MEHHP/MEHP	1.06	0.23	1.06	0.19	1.03	0.32	0.91	0.23
Model 3	MEHP + MEHHP	3.50	< 0.001*	2.83	< 0.001*	1.87	0.003	2.92	< 0.001*
Urinary metabolites		Cluster D/control (n = 5/143)		Cluster E/control (n = 4/143)		Cluster F/control (n = 21/143)
Urinary metabolites		OR	P-value^b	OR	P-value^b	OR	P-value^b
Model 1	MEHP	1.70	0.001*	1.79	0.02	1.57	0.004
Model 2	MEHHP	3.00	< 0.001*	3.42	< 0.001*	2.92	< 0.001*
	MEHHP/MEHP	0.99	0.89	1.10	0.16	1.04	0.35
Model 3	MEHP + MEHHP	2.95	< 0.001*	3.31	< 0.001*	2.75	< 0.001*

^a Multiple logistic regression, adjusted for age, BMI, atopy, education, and household income; the significance level (α) was set at 0.05

^b Multinomial logistic regression, adjusted for education and household income; to reduce the potential for type I errors in our multiple comparison study, we set the α level to 0.00238095 (0.05/21) using the Bonferroni correction method

*The model exhibited statistical significance