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Application of the proposed SERA-PLSR method for simultaneous determination of BIS and its metabolite in spiked human plasma
| Analytes | Conc. added (ng/mL) | Conc. found (ng/mL) | Mean Recovery % |
|---|---|---|---|
| BIS | 26 | 25.8 | 99.23 |
| 100 | 101 | 101.00 | |
| 236 | 240 | 101.69 | |
| Mean Recovery % ± RSD* | 100.64 ± 1.69 | ||
| Metabolite | 236 | 234 | 99.15 |
| 100 | 98.7 | 98.70 | |
| 26 | 25.6 | 98.46 | |
| Mean Recovery % ± RSD* | 98.77 ± 1.41 | ||
*Average of three determinations
